6241-30-1

Basic information

• Product Name: 3-(4-METHYL-PIPERIDIN-1-YL)-PROPYLAMINE
• Synonyms: 3-(4-methyl-1-piperidinyl)-1-propanamine(SALTDATA: FREE);4-Methyl-1-piperidinepropanamine 2HCl;N-AMINOPROPYL-4-PIPECOLINE;3-(4-METHYL-PIPERIDIN-1-YL)-PROPYLAMINE;3-(4-METHYLPIPERIDIN-1-YL)PROPAN-1-AMINE
• CAS NO: 6241-30-1
• Molecular Formula: C₉H₂₀N₂
• Molecular Weight: 156.27
• Mol File: 6241-30-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 222.8°C at 760 mmHg
• Flash Point: 84°C
• Appearance: /
• Density: 0.891±0.06 g/cm3(Predicted)
• Vapor Pressure: 0.0994mmHg at 25°C
• PKA: 10.44±0.10(Predicted)
• CAS DataBase Reference: 3-(4-METHYL-PIPERIDIN-1-YL)-PROPYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-METHYL-PIPERIDIN-1-YL)-PROPYLAMINE(6241-30-1)
• EPA Substance Registry System: 3-(4-METHYL-PIPERIDIN-1-YL)-PROPYLAMINE(6241-30-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 6241-30-1(Hazardous Substances Data)

Usage

General Description

3-(4-methyl-piperidin-1-yl)-propylamine, also known as MPPA or MPMPA, is a chemical compound with the molecular formula C11H24N2. It is a derivative of piperidine and is commonly used as a building block in the synthesis of various pharmaceuticals and organic compounds. MPPA is a clear, colorless liquid with a pungent odor and is slightly soluble in water. It is primarily used as a reagent in organic synthesis and as an intermediate in the production of pharmaceuticals, agrochemicals, and other fine chemicals. MPPA is considered to be a moderately hazardous substance and should be handled with care in a well-ventilated area and with appropriate personal protective equipment.

InChI:InChI=1/C9H20N2/c1-9-3-7-11(8-4-9)6-2-5-10/h9H,2-8,10H2,1H3/p+2

Upstream product

• 626-58-4 4-methylpiperidin 
• 4862-35-5 3-(4-methyl-piperidino)-propionitrile 

Downstream Products

• 1372589-72-4 N-[3-(4-methylpiperidin-1-yl)propyl]-3-{2-[(methylsulfonyl)amino]phenyl}-11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepine-8-carboxamide 
• 1314161-94-8 C₂₈H₄₁N₃O₄S 
• 103094-26-4 4-(2-Fluoro-phenyl)-1,3-dimethyl-5-[3-(4-methyl-piperidin-1-yl)-propylamino]-1,7-dihydro-pyrazolo[3,4-b]pyridin-6-one 
• 85723-32-6 N-[4-(2-Fluoro-benzoyl)-2,5-dimethyl-2H-pyrazol-3-yl]-2-[3-(4-methyl-piperidin-1-yl)-propylamino]-acetamide 

Relevant articles and documents

Design, synthesis and biological evaluation of 1,3-diaminopropanes: A new class of polyamine analogs as leishmanicidal agents

Analogs of 1,3-diaminopropane as inhibitors for the growth of Leishmania donovani have been synthesized and evaluated for their antileishmanial activity. Of the many active compounds, 1-(3-N,N-bis methoxycarbonyl guanidino)propyl-4- methylpiperidine piperazine (4e,f) exhibited significant in vivo inhibitory efficacy against L. donovani by oral and intraperitoneal route of administration.