62410-93-9

Basic information

• Product Name: PGE2-1,15-lactone
• Synonyms: (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-diene-1-oic acid 1,15-lactone;(5Z,13E,15S)-11α,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid 1,15-lactone;(5Z,13E,15S)-9-Oxo-11α,15-dihydroxyprosta-5,13-diene-1-oic acid 1,15-lactone;(5Z,8R,13E,15S)-11α,15-Dihydroxy-9-oxoprosta-5,13-diene-1-oic acid 1,15-lactone;PGE2-1,15-lactone
• CAS NO: 62410-93-9
• Molecular Formula: C20H30O4
• Molecular Weight: 334.453
• Mol File: 62410-93-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 499.4°Cat760mmHg
• Flash Point: 269.9°C
• Appearance: /
• Density: 1.111g/cm³
• Vapor Pressure: 4.58E-12mmHg at 25°C
• Refractive Index: 1.561
• CAS DataBase Reference: PGE2-1,15-lactone(CAS DataBase Reference)
• NIST Chemistry Reference: PGE2-1,15-lactone(62410-93-9)
• EPA Substance Registry System: PGE2-1,15-lactone(62410-93-9)

Safety Data

• Hazardous Substances Data: 62410-93-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H30O4/c1-2-3-7-10-16(22)12-13-18-17(19(23)15-20(18)24)11-8-5-4-6-9-14-21/h5,8,12-18,22-23H,2-4,6-7,9-11H2,1H3/b8-5-,13-12+/t16-,17+,18+/m0/s1

Upstream product

• 62410-95-1 PGE₂ 1,15-lactone 11-(trimethylsilyl ether) 
• 276241-85-1 (3S,11aR,14R,14aR)-14-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}-3-pentyl-6,7,8,11,11a,13,14,14a-octahydro-3H-cyclopenta[e]oxacyclotridecine-5,12-dione 
• 318234-63-8 (3S,11aR,14R,14aR)-14-hydroxy-3-pentyl-9,10-didehydro-6,7,8,11,11a,13,14,14a-octahydro-3H-cyclopenta[e]oxacyclotridecine-5,12-dione 
• 61305-35-9 (R)-4-((tert-butyldimethylsilyl)oxy)cyclopent-2-enone 
• 276241-82-8 (2R,3R,4R)-4-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}-2-(2-butynyl)-3-[(E,3S)-3-hydroxy-1-octenyl]cyclopentan-1-one 
• 276241-84-0 (3S,11aR,14R,14aR)-14-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}-3-pentyl-9,10-didehydro-6,7,8,11,11a,13,14,14a-octahydro-3H-cyclopenta[e]oxacyclotridecine-5,12-dione 
• 276241-81-7 (2R,3R,4R)-4-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}-2-(2-butynyl)-3-{(E,3S)-3-[(1,1,1-triethylsilyl)oxy]-1-octenyl}cyclopentan-1-one 
• 183073-00-9 (1S,2E)-1-pentyl-3-(1,1,1-tributylstannyl)-2-propenyl (1,1,1-triethylsilyl) ether 
• 276241-83-9 (1S,2E)-3-[(1R,2R,5R)-5-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}-2-(2-butynyl)-3-oxocyclopentyl]-1-pentyl-2-propenyl 5-heptynoate 
• 32556-71-1 1-octyn-3-ol 
• 944269-19-6 (3S)-triethylsilyl-1-oxyoctyne 
• 55314-49-3 PGF_2α 1,15-lactone 
• 363-24-6 dinoprostone 
• 62410-94-0 (4E,12Z)-(1S,3R,3aR,6S,14aR)-1-Hydroxy-6-pentyl-3-trimethylsilanyloxy-1,2,3,3a,6,9,10,11,14,14a-decahydro-7-oxa-cyclopentacyclotridecen-8-one 

Relevant articles and documents

Novel and flexible entries into prostaglandins and analogues based on ring closing alkyne metathesis or alkyne cross metathesis

The suitably functionalized cyclopentanone derivatives 12, 13, 19, and 37 serve as common precursors for the synthesis of various prostaglandins, prostaglandin-1,15-lactones, and unnatural analogues thereof. All of them contain a 2-butynyl entity which is

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