62420-83-1Relevant articles and documents
A Dieckmann/ring expansion approach to tetrahydropyrido- and tetrahydroazepino-[1,2-a]indoles
Bit,Davis,Hill,Keech,Vesey
, p. 4645 - 4664 (1991)
A general Dieckmann/ring expansion approach to fused[1,2-a]indole systems is reported. This approach has allowed the synthesis of a large variety of substituted systems required for the preparation of a series of potent and selective inhibitors of Protein Kinase C.
AMINOPYRIMIDINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF
-
Paragraph 253, (2021/12/12)
Provided herein are novel compounds, for example, compounds having a Formula (I) or Formula (II), or a pharmaceutically acceptable salt thereof. Also provided herein are methods of preparing the compounds and methods of using the compounds, for example, for treating various cancer described herein, such as lung cancer (e.g., non-small cell lung cancer).
FUSED-RING OR TRICYCLIC ARYL PYRIMIDINE COMPOUND USED AS KINASE INHIBITOR
-
Paragraph 0229; 0237; 0238; 0274; 0275, (2018/03/25)
Disclosed is a fused-ring or tricyclic aryl pyrimidine compound used as a mutation selectivity EGFR inhibitor. Specifically, disclosed is a compound represented by formula (I) and used as an EGFR inhibitor or a pharmaceutically acceptable salt thereof.