62436-68-4 Usage
Main properties
1. Chemical name: 2-Propenoic acid, 2-(acetylamino)-3-phenyl-, 1-methylethyl ester, (Z)
2. Common name: Ibuprofen
3. Type: Nonsteroidal anti-inflammatory drug (NSAID)
4. Uses: Relieve pain and reduce inflammation
5. Mechanism of action: Inhibits the production of prostaglandins
6. Conditions treated: Arthritis, menstrual cramps, headaches, minor injuries
7. Availability: Over-the-counter and prescription-strength formulations
8. Safety: Generally considered safe and effective when used as directed
9. Risks: Long-term or high-dose use can increase risk of gastrointestinal bleeding, heart attack, and stroke
Specific content
1. Chemical name: 2-Propenoic acid, 2-(acetylamino)-3-phenyl-, 1-methylethyl ester, (Z)
2. Common name: Ibuprofen
3. Type: Nonsteroidal anti-inflammatory drug (NSAID)
4. Uses: Used to relieve pain and reduce inflammation
5. Mechanism of action: Works by inhibiting the production of prostaglandins
6. Conditions treated: Arthritis, menstrual cramps, headaches, minor injuries
7. Availability: Available over-the-counter and in prescription-strength formulations
8. Safety: Generally considered safe and effective when used as directed
9. Risks: Long-term or high-dose use can increase the risk of gastrointestinal bleeding, heart attack, and stroke.
Check Digit Verification of cas no
The CAS Registry Mumber 62436-68-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,4,3 and 6 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 62436-68:
(7*6)+(6*2)+(5*4)+(4*3)+(3*6)+(2*6)+(1*8)=124
124 % 10 = 4
So 62436-68-4 is a valid CAS Registry Number.
62436-68-4Relevant academic research and scientific papers
Chen, Jianzhong,Gridnev, Ilya D.,Hu, Yawen,Li, Bowen,Zhang, Wanbin,Zhang, Zhenfeng
, p. 5371 - 5375 (2020)
Earth-abundant nickel, coordinated with a suitable chiral bisphosphine ligand, was found to be an efficient catalyst for the asymmetric hydrogenation of 2-amidoacrylates, affording the chiral α-amino acid esters in quantitative yields and excellent enantioselectivity (up to 96 % ee). The active catalyst component was studied by NMR and HRMS, which helped us to realize high catalytic efficiency on a gram scale with a low catalyst loading (S/C=2000). The hydrogenated products could be simply converted into chiral α-amino acids, β-amino alcohols, and their bioactive derivatives. Furthermore, the catalytic mechanism was investigated using deuterium-labeling experiments and computational calculations.
