62458-92-8

Basic information

• Product Name: 2-AMino-7-benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyriMidin-4-one
• Synonyms: 2-AMino-7-benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyriMidin-4-one;2-AMino-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyriMidin-4(3H)-one
• CAS NO: 62458-92-8
• Molecular Formula: C₁₄H₁₆N₄O
• Molecular Weight: 256.30304
• EINECS: -0
• Mol File: 62458-92-8.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-AMino-7-benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyriMidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMino-7-benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyriMidin-4-one(62458-92-8)
• EPA Substance Registry System: 2-AMino-7-benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyriMidin-4-one(62458-92-8)

Safety Data

• Hazardous Substances Data: 62458-92-8(Hazardous Substances Data)

Usage

Chemical structure

2-Amino-7-benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one is a pyrido[3,4-d]pyrimidin-4-one derivative, which means it contains a pyrido[3,4-d]pyrimidin-4-one core structure.

Pharmacological properties

The compound has potential pharmacological properties, which means it may have applications in drug development and medicinal chemistry.

Biological activity

The compound's biological activity and potential uses are not yet fully understood, and further studies are needed to investigate its effects.

Research tool

The compound could be used as a research tool to investigate the potential therapeutic effects of compounds with similar structures.

Molecular target

The compound may be useful in the design of molecules targeting specific biological pathways or receptors.

Upstream product

• 124-46-9 guanidine hydrogen carbonate 
• 52763-21-0 ethyl 1-benzyl-3-oxopiperidine-4-carboxylate hydrochloride 
• 50-01-1 guanidine hydrochloride 
• 882182-30-1 ethyl N-benzyl-3-oxo-4-piperidinecarboxylate hydrochloride 
• 593-85-1 diguanidine carbonate 

Downstream Products

• 859825-79-9 7-benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-amine 
• 1449500-86-0 7-benzyl-N⁴-butyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-2,4-diamine 
• 1449500-87-1 C₃₃H₄₉N₅O₆ 
• 1449500-11-1 (2-amino-4-(butylamino)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl)(phenyl)methanone 
• 570415-48-4 6-benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine 

Relevant articles and documents

Design and synthesis of tetrahydropyridopyrimidine based Toll-Like Receptor (TLR) 7/8 dual agonists

In a continuing effort to discover novel TLR agonists, herein we report on the discovery and structure–activity relationship of novel tetrahydropyridopyrimidine TLR 7/8 agonists. Optimization of this series towards dual agonist activity and a high clearance profile resulted in the identification of compound 52a1. Evaluation in vivo revealed an interferon stimulated response (ISG) in mice with limited systemic exposure and demonstrated the potential in antiviral treatment or as a vaccine adjuvant.

Piperidino-pyrimidine derivatives for the treatment of viral infections

This invention relates to piperidino-pyhmidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.

BICYCLOHETEROARYLAMINE COMPOUNDS AS ION CHANNEL LIGANDS AND USES THEREOF

Amine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, includin