62458-92-8

Usage

Chemical structure

2-Amino-7-benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one is a pyrido[3,4-d]pyrimidin-4-one derivative, which means it contains a pyrido[3,4-d]pyrimidin-4-one core structure.

Pharmacological properties

The compound has potential pharmacological properties, which means it may have applications in drug development and medicinal chemistry.

Biological activity

The compound's biological activity and potential uses are not yet fully understood, and further studies are needed to investigate its effects.

Research tool

The compound could be used as a research tool to investigate the potential therapeutic effects of compounds with similar structures.

Molecular target

The compound may be useful in the design of molecules targeting specific biological pathways or receptors.

Upstream product

• 50-01-1 guanidine hydrochloride 
• 52763-21-0 ethyl 1-benzyl-3-oxopiperidine-4-carboxylate hydrochloride 
• 882182-30-1 ethyl N-benzyl-3-oxo-4-piperidinecarboxylate hydrochloride 
• 124-46-9 guanidine hydrogen carbonate 
• 593-85-1 diguanidine carbonate 

Downstream Products

• 859825-79-9 7-benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-amine 
• 1449500-86-0 7-benzyl-N⁴-butyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-2,4-diamine 
• 1449500-87-1 C₃₃H₄₉N₅O₆ 
• 1449500-11-1 (2-amino-4-(butylamino)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl)(phenyl)methanone 
• 570415-48-4 6-benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine 

Relevant academic research and scientific papers

Design and synthesis of tetrahydropyridopyrimidine based Toll-Like Receptor (TLR) 7/8 dual agonists

In a continuing effort to discover novel TLR agonists, herein we report on the discovery and structure–activity relationship of novel tetrahydropyridopyrimidine TLR 7/8 agonists. Optimization of this series towards dual agonist activity and a high clearance profile resulted in the identification of compound 52a1. Evaluation in vivo revealed an interferon stimulated response (ISG) in mice with limited systemic exposure and demonstrated the potential in antiviral treatment or as a vaccine adjuvant.

P2X7 MODULATORS

The present invention is directed to a compound of Formula (I) The invention also relates to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) are also within the scope of the invention.

Piperidino-pyrimidine derivatives for the treatment of viral infections

This invention relates to piperidino-pyhmidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.

PIPERIDINO-PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS

This invention relates to piperidino-pyhmidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.

BICYCLOHETEROARYLAMINE COMPOUNDS AS ION CHANNEL LIGANDS AND USES THEREOF

Amine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, includin

Rho-kinase inhibitors

Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., c