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Methyl 11-cis,14-cis,17-cis-eicosatrienoate, also known as 11(Z),14(Z),17(Z)-Eicosatrienoic acid methyl ester, is a rare omega-3 polyunsaturated fatty acid (PUFA) found in normal humans. It is an ester version of the free acid, which is one of the most active essential fatty acids when tested for the inhibition of fatty acid elongation/desaturation reactions. These reactions convert dietary C-18 fatty acids to C-20 eicosanoid precursors, which are important for various physiological functions.

62472-96-2

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62472-96-2 Usage

Uses

Used in Nutritional Supplements:
Methyl 11-cis,14-cis,17-cis-eicosatrienoate is used as a nutritional supplement for providing essential omega-3 fatty acids. It is particularly beneficial for individuals who may not be getting enough omega-3 PUFAs from their diet, as it helps support overall health and well-being.
Used in Pharmaceutical Formulations:
In the pharmaceutical industry, Methyl 11-cis,14-cis,17-cis-eicosatrienoate is used as an active ingredient in the development of drugs targeting fatty acid metabolism. Its ability to inhibit fatty acid elongation/desaturation reactions makes it a promising candidate for the treatment of conditions related to lipid metabolism dysregulation.
Used in Research Applications:
Methyl 11-cis,14-cis,17-cis-eicosatrienoate is also used as a research tool in the study of fatty acid metabolism, eicosanoid production, and their roles in various physiological processes. It can help researchers better understand the mechanisms underlying these processes and develop targeted therapies for related conditions.
Used in Functional Foods:
In the food industry, Methyl 11-cis,14-cis,17-cis-eicosatrienoate can be incorporated into functional foods as a source of omega-3 PUFAs. These foods can provide health benefits beyond basic nutrition, such as supporting heart health, brain function, and reducing inflammation.

Check Digit Verification of cas no

The CAS Registry Mumber 62472-96-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,4,7 and 2 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 62472-96:
(7*6)+(6*2)+(5*4)+(4*7)+(3*2)+(2*9)+(1*6)=132
132 % 10 = 2
So 62472-96-2 is a valid CAS Registry Number.

62472-96-2Relevant articles and documents

Chemical C2-elongation of polyunsaturated fatty acids

Kuklev, Dmitry V.,Smith, William L.

, p. 172 - 177 (2007/10/03)

Three fatty acids were synthesized from commercially available α-linolenic, stearidonic and eicosapentaenoic acids by C2-elongation using a four step preparative technique. The parent fatty acid methyl esters were reduced to alcohols with LiAlH4, converted to bromides by treatment with triphenylphosphine dibromide, coupled with a lithiated C2-elongation block - 2,4,4-trimethyl-2-oxazoline - to form the corresponding 2,2-dimethyloxazolines of C2-elongated fatty acids, and finally, converted to the target polyunsaturated fatty acids by acidic alcoholysis. Yields of more than 60% were achieved on a gram scale. The resulting 11Z,14Z,17Z-eicosatrienoic, 8Z,11Z,14Z,17Z-eicosatetraenoic and 7Z,10Z,13Z,16Z,19Z-docosapentaenoic acids were obtained as colorless oils with >98% purity and could be used for biochemical investigations without additional purification. The elongated fatty acids were free of byproducts that could result from Z-E isomerization or migration of double bonds.

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