625110-45-4

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 625110-43-2 [4-[1,3]dioxan-2-yl-(1S)-(3-fluorobenzyl)-2-oxo-butyl]carbamic acid tert-butyl ester 
• 478698-84-9 N'-methoxy-N'-methyl (S)-N-BOC-(3-fluorophenyl)-alanine amide 
• 33884-43-4 2-(2-Bromoethyl)-1,3-dioxane 

Relevant academic research and scientific papers

Process research on [(2S)-(3-fluorophenyl)-(1S)-(5-oxotetrahydrofuran-2-yl) ethyl]carbamic acid tert-butyl ester, a lactone intermediate for an aspartyl protease inhibitor

Two processes for the preparation of lactone [2S-(3-fluorophenyl)-1S-(5- oxotetrahydrofuran-2-yl)ethyl]carbamic acid tert-butyl ester 1 starting from S-BOC-(3-fluorophenyl)alanine 3 are described. (S)-(3-Fluorophenyl)alanine N-methyl-N-methoxy amide 10, t

METHODS FOR MANUFACTURE OF DIHYDRO-FURAN-2-ONE DERIVATIVES

This invention relates to dihydro-furan-2-one derivatives, their intermediates and methods of manufacture. As such, the present invention includes methods of making a compound of the formula (V-1), wherein R2 and p are herein defined. The prese