62522-92-3Relevant academic research and scientific papers
Palladium-Catalyzed Aminocarbonylation in Solid-Phase Peptide Synthesis: A Method for Capping, Cyclization, and Isotope Labeling
Skogh, Anna,Friis, Stig D.,Skrydstrup, Troels,Sandstr?m, Anja
supporting information, p. 2873 - 2876 (2017/06/07)
A new synthetic approach for introducing N-capping groups onto peptides attached to a solid support, combining aminocarbonylation under mild conditions using a palladacycle precatalyst and solid-phase peptide synthesis, is reported. The use of a silacarboxylic acid as an in situ CO-releasing molecule allowed the reaction to be performed in a single vial. The method also enables versatile substitution of side chains, side-chain-to-side-chain cyclizations, and selective [13C] acyl labeling of modified peptides.
Electronic effect of prolinate ligand-dirhodium(ii) complexes on catalytic asymmetric dipolar cycloaddition
Ishitani, Hitoshi,Achiwa, Kazuo
, p. 153 - 156 (2007/10/03)
We prepared several efficient chiral N-benzoylpyrroridinecarboxylic acid ligands for dirhodium-catalyzed asymmetric dipolar cycloaddition and found that the electronic effect of the dirhodium(II) complexes influenced the catalytic activity, and the electr
Steric and electronic effects of substrates and rhodium chiral catalysts in asymmetric cyclopropanation
Yoshikawa,Achiwa
, p. 2048 - 2053 (2007/10/03)
We have prepared several new, efficient, chiral N-acyl pyrrolidine carboxylic acid ligands for dirhodium-catalyzed asymmetric cyclopropanation and found that the steric and electronic effects of the rhodium(II) complexes and substrates influenced the enan
