62558-39-8

Upstream product

• 364-32-9 4-fluoro-2,6-dinitrophenol 
• 371-41-5 4-Fluorophenol 

Downstream Products

• 68200-49-7 Dimethyl-thiocarbamic acid S-[2-(2-dimethylcarbamoylsulfanyl-5-fluoro-3-nitro-phenyldisulfanyl)-4-fluoro-6-nitro-phenyl] ester 
• 82366-46-9 N-methyl-4-fluoro-2,6-dinitroaniline 
• 861107-04-2 4-fluoro-2,6-dinitrobenzonitrile 
• 939037-10-2 dimethyl 2-(4-fluoro-2,6-dinitrophenyl)malonate 
• 372-41-8 5-fluoro-1,3-phenylenediamine 

Relevant academic research and scientific papers

Synthesis of 6-aminobenzopentathiepines by reactions of 4-nitrobenzodithiol-2-ones with NaHS

The reactions of benzodithiol-2-ones containing a 4-nitro group with NaHS led to mixtures of 6- aminobenzopentathiepines and 4-nitrobenzotrithiols. The product ratio and yields depend on the substituent in the aromatic ring. Based on the yields of benzopentathiepines, the following series of substituent efficiency can be inferred: CF3 ? F, Cl > CN. Aminobenzopentathiepines are probably formed via the intermediate benzotrithiols; the transformation apparently starts with the reduction of the nitro group.

SUBSTITUTED ARYLSULFONAMIDES AS ANTIVIRAL AGENTS

The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particu

NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS

There is provided a CRF receptor antagonist comprising a compound of the formula (I): wherein, ring A is a 5-membered ring represented by the formula (A'): wherein X is a carbon and X is an oxygen, a sulfur or - NR -,or formula (A"): wherein X is a nitrogen and R is an optionally substituted hydrocarbyl, Ris an amino substituted by two optionally substituted hydrocarbyl groups, Ris an phenyl, Y is CR or a nitrogen, Y is CRor a nitrogen and Yis CRor a nitrogen, provided that one or less of Y, Y, and Y is nitrogen, W is a bond, -(CH2)n-, and Z is a bond, -NR -,etc.; or a salt thereof or a prodrug thereof.

1-BENZYL-5-PIPERAZIN-1-YL-3,4 DIHYDRO-1H-QUINAZOLIN-2-ONE DERIVATIVES AND THE RESPECTIVE 1H-BENZO(1,2,6)THIADIAZINE-2,2-DIOXIDE AND 1,4-DIHYDRO-BENZO(D) (1,3)OXAZIN-2-ONE DERIVATIVES AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR (5-HT) FOR THE TREATME

The invention relates to substituted quinazolinone compunds of formula (I) or a pharmaceutically acceptable salt thereof, wherein Y is C or S; m is 1 when Y is C and m is 2 when Y is S; n is 1 or 2; p is from 0 to 3; q is from 1 to 3; Z is -(CRa/sup