82366-46-9Relevant academic research and scientific papers
NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS
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Page/Page column 159-160, (2010/02/11)
There is provided a CRF receptor antagonist comprising a compound of the formula (I): wherein, ring A is a 5-membered ring represented by the formula (A'): wherein X is a carbon and X is an oxygen, a sulfur or - NR -,or formula (A"): wherein X is a nitrogen and R is an optionally substituted hydrocarbyl, Ris an amino substituted by two optionally substituted hydrocarbyl groups, Ris an phenyl, Y is CR or a nitrogen, Y is CRor a nitrogen and Yis CRor a nitrogen, provided that one or less of Y, Y, and Y is nitrogen, W is a bond, -(CH2)n-, and Z is a bond, -NR -,etc.; or a salt thereof or a prodrug thereof.
EFFECT OF STRUCTURE ON THE BASICITY OF AROMATIC AMINES
Kuznetsov, L. L.,Gidaspov, B. V.
, p. 595 - 601 (2007/10/02)
The basicity of a series of primary, secondary, and tertiary aromatic amines ( with pKbH between ca. -1 and ca. -10) was measured by spectrophotometric method.The obtained data were used to calculate the correlation equations relating the basic
