6256-05-9

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 14737-89-4 3,4-dimethoxy-trans-cinnamic acid 
• 2033-89-8 3,4-dimethoxyphenol 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 2316-26-9 3,4-dimethoxycinnamic acid 
• 20583-78-2 ethyl (E)-3,4-dimethoxycinnamate 
• 94774-01-3 3,3-Bis-(3,4-dimethoxy-phenyl)-propionic acid ethyl ester 

Downstream Products

• 111222-55-0 3-(3,4-dimethoxyphenyl)-5,6-dimethoxyindan-1-one 
• 94773-74-7 [2,2-Bis-(3,4-dimethoxy-phenyl)-ethylcarbamoyloxy]-acetic acid ethyl ester 
• 104020-88-4 3-{1-Benzyl-3-[2-(3,4-dimethoxy-phenyl)-2-phenyl-ethyl]-ureido}-propionic acid ethyl ester 
• 104020-90-8 3-{1-Benzyl-3-[2,2-bis-(3,4-dimethoxy-phenyl)-ethyl]-ureido}-2-methyl-propionic acid ethyl ester 
• 104020-91-9 1-Benzyl-3-[2-(3,4-dimethoxy-phenyl)-2-phenyl-ethyl]-4-hydroxy-tetrahydro-pyrimidin-2-one 
• 104020-93-1 1-Benzyl-3-[2,2-bis-(3,4-dimethoxy-phenyl)-ethyl]-4-hydroxy-5-methyl-tetrahydro-pyrimidin-2-one 
• 94773-79-2 (6R,10bS)-6-(3,4-Dimethoxy-phenyl)-8,9-dimethoxy-1,5,6,10b-tetrahydro-oxazolo[4,3-a]isoquinolin-3-one 
• 15547-44-1 1-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-indene 
• 104151-29-3 cis-3-(3,4-dimethoxyphenyl)-1-methyl-5,6-dimethoxyindane 
• 102553-71-9 1-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-3-methyl-indene 

Relevant academic research and scientific papers

Modular Approach to 9-Monosubstituted Fluorene Derivatives Using MoV Reagents

Oxidative coupling using molybdenum(V) reagents provides fast access to highly functionalized 9-monosubstituted fluorenes. This synthetic approach is highly modular, is high yielding, and tolerates a variety of labile moieties, e.g. amides or iodo groups. The established protocol leads to promising precursors for pharmacologically important analogues of melatonin.

A STEREOSELECTIVE SYNTHESIS OF 5-ARYL- AND 6-ARYLOXAZOLOISOQUINOLINES

Reduction of N-(α,β-diaryl)ethyl and N-(β,β-diaryl)ethyl ethoxycarbonylmethyl carbamates, obtained from the corresponding 2,3-diaryl- and 3,3-diarylpropionic acids, with diisobutylaluminum hydride, followed by cyclization with formic acid at room temperature gave the corresponding 5-aryl and 6-aryl-oxazoloisoquinolines, respectively, with high stereoselectivity.