62567-91-3

Upstream product

• 611-06-3 2,4-dichloronitrobenzene 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 22908-28-7 (5-chloro-2-nitro-phenyl)-acetic acid 
• 2516-95-2 5-chloro-2-nitrobenzoic acid 
• 62567-94-6 Ethyl-2-nitro-5-chlorbenzoylformiat 
• 1403589-45-6 4-((furan-2-yl)-6-phenyl-9-β-D-ribofuranosyl)-9H-pyrimido[4,5-b]indole 
• 1403589-42-3 4-(furan-2-yl)-6-phenyl-9-(2,3,5-tri-O/-benzoyl-β-D-ribofuranosyl)-9H-pyrimido[4,5-b]indole 
• 1403589-24-1 4-(furan-2-yl)-6-(furan-3-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole 
• 1403589-41-2 4,6-bis(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole 
• 1403589-39-8 6-chloro-4-phenyl-β-D-ribofuranosyl-9H-pyrimido[4,5-b]indole 
• 1403589-32-1 6-chloro-4-phenyl-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole 
• 1403589-31-0 4-(benzofuran-2-yl)-6-chloro-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole 
• 1403589-30-9 6-chloro-4-(thiophen-3-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole 
• 1403589-29-6 6-chloro-4-(thiophen-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole 
• 1403589-28-5 6-chloro-4-(furan-3-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole 
• 1403589-27-4 6-chloro-4-(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole 

Relevant academic research and scientific papers

Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides

A series of new pyrimido[4,5-b]indole ribonucleosides bearing phenyl or hetaryl group at position 4 has been prepared by selective Pd-catalyzed cross-coupling reactions of the corresponding protected 4,6-dichloropyrimido[4, 5-b]indole ribonucleoside with (het)arylboronic acids or stannanes followed by deprotection. Further cross-couplings under harsher conditions and employing X-Phos ligand proceeded at the position 6 leading to 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides. Some of these compounds displayed antiviral activity against Dengue virus.

Ethyl cyanoacetate: A new cyanating agent for the palladium-catalyzed cyanation of aryl halides

A new Pd-catalyzed cyanation reaction has been discovered using ethyl cyanoacetate as the cyanating reagent. A variety of electron-rich and electron-deficient aryl halides were efficiently converted into their corresponding nitriles in good to excellent yields.