62576-13-0Relevant academic research and scientific papers
Reactions of 2-unsubstituted 1H-imidazole 3-oxides with 2,2-bis(trifluoromethyl)ethene-1,1-dicarbonitrile: A stepwise 1,3-dipolar cycloaddition
Mloston, Grzegorz,Jasinski, Marcin,Linden, Anthony,Heimgartner, Heinz
, p. 1304 - 1316 (2007/10/03)
The reaction of 1,4,5-trisubstituted 1H-imidazole-3-oxides 1 with 2,2-bis(trifluoromethyl)ethene-1,1-dicarbonitrile (7, BTF) yielded the corresponding 1,3-dihydro-2H-imidazol-2-ones 10 and 2-(1,3-dihydro-2H-imidazol- 2-vlidene)malononitriles 11, respectiv
Novel imidazoles and hydantoins moderately strained by incorporation with 2-azabicyclo[2.2.1]heptene skeleton
Kobayashi,Fujieda,Murakami,Nakamura,Ono,Yamamoto,Kato
, p. 3082 - 3087 (2007/10/02)
The reactions of 3-acyl-2-azabicyclo[2.2.1]hept-5-enes with phenyl isocyanate, phenyl isothiocyanate, and ethoxycarbonyl isothiocyanate followed by cyclization reactions under basic conditions respectively provided a hydantoin, a thiohydantoin, and a 1,3-
Carboxylate protection for the synthesis of 4,5-disubstituted 1-methylimidazoles
Shapiro,Gomez-Lor
, p. 5524 - 5526 (2007/10/02)
Using the carboxylate function as a readily removed blocking group for the 2-position, a regioselective synthesis of diverse 4,5-disubstituted 1-methylimidazoles has been developed starting from 1-methyltribromoimidazole, 5.
