6258-05-5

Usage

Chemical structure

A derivative of pyrrolidine with an amine and an ethyl group attached

Applications

a. Synthesis of various pharmaceuticals and organic compounds
b. Potential candidate for drug development due to its pharmacological properties
c. Research and development of new chemical entities

Safety precautions

Requires careful handling and proper safety measures in laboratory settings due to its complex molecular structure

InChI:InChI=1/C8H19N3/c9-3-4-10-5-8-11-6-1-2-7-11/h10H,1-9H2

Upstream product

• 7250-67-1 1-(2-chloroethyl)pyrrolidine hydrochloride 
• 107-15-3 ethylenediamine 

Relevant academic research and scientific papers

Dehydrogenative Coupling of Ethanol and Ester Hydrogenation Catalyzed by Pincer-Type YNP Complexes

The "Y" donor group (Y = -OMe, -SEt, -PPh2, -NH2, -NMe2, -Py, pyrrolidinyl, quinolyl) of the pincer-type ruthenium complexes RuHCl(CO)[κ3-YNP] has a dramatic influence on the catalytic activity in the dehydrogenative homocoupling and cross-coupling of ethanol and ester hydrogenation reactions. The observations are connected with the mechanisms of the catalytic reactions, and this paper provides evidence for ester C-O bond formation/cleavage assisted by the bifunctional catalysts in an outer-sphere fashion, reminiscent of the Tishchenko chemistry.

DIUREA DERIVATIVES

The present invention relates to novel diurea derivatives that block intracellular signal transduction and thereby inhibit the production of pro-inflammatory cytokines, especially interleukin-2 (IL-2) and/or induce apoptosis in activated T-cells. It further discloses such a compound for use as a medicament, the use of said compound for the manufacturing of a medicament for the treatment of immune disorders which benefit from inhibition of production of IL-2 and other pro-inflammatory cytokines and/or induction of apoptosis in activated T-cells, a pharmaceutical composition comprising said compound and a method of treatment comprising administration of a pharmaceutically effective amount of said compound. A compound of the general formula I.