62596-61-6Relevant academic research and scientific papers
The importance of 1,2-anti-disubstitution in monotosylated diamine ligands for ruthenium(II)-catalysed asymmetric transfer hydrogenation
Hayes, Aidan,Clarkson, Guy,Wills, Martin
, p. 2079 - 2084 (2007/10/03)
The synthesis and applications to transfer hydrogenation of three derivatives of the popular TsDPEN are described. The results clearly demonstrate the importance of both disubstitution and the anti arrangement of substituents on this ligand. An explanatio
Influence of Phenylthio and Alkylthio Substituents on the Reactivity of 1-Oxa-1,3-butadienes in Hetero Diels-Alder Reactions
Tietze, Lutz F.,Fennen, Jens,Wichmann, Juergen
, p. 1507 - 1512 (2007/10/02)
The synthesis of the cyclic enamino ketones 1-3 bearing an alkylthio or an phenylthio group and their reactivity in hetero Diels-Alder reactions with enol ethers is described.Only compound 3 with an phenylthio group undergoes a cycloaddition with 16a-d to afford the diastereomeric adducts 17a-d and 18a-d.To estimate the activation by a phenylthio and alkylthio group semiempirical PM3/RHF calculations of the frontier orbital energies and coefficients of different enamine carbaldehydes have been performed.Key Words: Enamino ketones / 1,4-Thiazines / Hetero Diels-Alder reactions / Pyrans, dihydro / Calculations, semiempirical
