62600-73-1Relevant articles and documents
Asymmetric synthesis of α-bromohydrins by carrot root as biocatalyst and conversion to enantiopure β-hydroxytriazoles and styrene oxides using click chemistry and SN2 ring-closure
Hosseinzadeh, Rahman,Mohadjerani, Maryam,Mesgar, Sakineh
, p. 583 - 591 (2019/02/17)
In this study we have combined the bioreduction of α-bromoketones using carrot root as biocatalyst and click chemistry for the preparation of enantiopure β-hydroxytriazoles in excellent enantiomeric excesses and yields. Moreover, we have utilized chiral α-halohydrins for the synthesis of enantiopure styrene oxides in very good yields and enantiomeric excesses. Structural assignments of the products were based on their 1H and 13C NMR data and their optical rotations. The enantiomeric excess of the chiral products was obtained by HPLC analysis.
Stereoselective epoxidation of alkenes with hydrogen peroxide using a bipyrrolidine-based family of manganese complexes
Garcia-Bosch, Isaac,Gomez, Laura,Polo, Alfonso,Ribas, Xavi,Costas, Miquel
supporting information; experimental part, p. 65 - 70 (2012/03/27)
Novel manganese complexes containing N4-tetradentate ligands derived from chiral bipyrrolidinediamines catalyze the stereoselective epoxidation of a wide array of alkenes using low catalyst loadings (0.1 mol%) and hydrogen peroxide (1.2 equiv.) as terminal oxidant. This family of catalysts affords good to excellent yields (80-100%) and moderate to good ees (40-73%) in short reaction times (30 min) making efficient use of hydrogen peroxide.
Asymmetric epoxidation of styrenes catalyzed by molybdenum complexes with amino alcohol ligands
Wang, Yi,Wu, Zhiqing,Li, Zhengkai,Zhou, Xiang-Ge
experimental part, p. 2509 - 2511 (2009/09/05)
Two common amino alcohols, prolinol and isolucinol, and their derivatives have been screened to coordinate with MoO2(acac)2 to form in situ catalysts for asymmetric epoxidation of styrenes with the highest enantioselectivity of 84% for 4-fluoro-styrene under the optimized reaction conditions.