62604-37-9Relevant academic research and scientific papers
Copper-mediated coupling of boronic acids, amines, and carbon disulfide: An approach to organic dithiocarbamates
Qi, Chaorong,Guo, Tianzuo,Xiong, Wenfang
supporting information, p. 2626 - 2630 (2016/11/11)
An efficient copper-mediated three-component coupling reaction of boronic acids, amines, and carbon disulfide has been developed, which provides a new approach to a wide range of functionalized dithiocarbamates in good to excellent yields. The present methodology has many advantages, such as mild reaction conditions, easily available substrates, wide substrate scope, and high functional-group tolerance.
A method for the synthesis of thio-carbamate
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Paragraph 0140; 0141; 0142; 0143; 0144; 0145; 0146-0148, (2016/10/10)
The invention belongs to the technical field of chemical synthesis and discloses a dithiocarbamate synthesis method. The dithiocarbamate synthesis method comprises that in an organic solvent, Ar-B(OH)2, NHR1R2 and carbon disulfide as raw materials and a copper salt and alkali as promoters undergo a reaction at a temperature of 60-120 DEG C for 10-24h with stirring, after the reaction, the reaction product is cooled to a room temperature, then is filtered and then is subjected to reduced pressure distillation for solvent removal so that a crude product is obtained, and the crude product is purified by column chromatography so that dithiocarbamate is obtained. The dithiocarbamate synthesis method realizes dithiocarbamate synthesis by one step, has simple and easy processes and a high product yield, utilizes cheap and easily available raw materials, has a low synthesis cost and has great industrial production values.
