62605-69-0

Basic information

• Product Name: 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propane-1-sulfonyl chloride
• Synonyms: 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propane-1-sulfonyl chloride;3-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-propanesulfonyl chloride
• CAS NO: 62605-69-0
• Molecular Formula: C₁₁H₁₀ClNO₄S
• Molecular Weight: 287.7194
• Mol File: 62605-69-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 432.3±28.0 °C(Predicted)
• Appearance: /
• Density: 1.521±0.06 g/cm3(Predicted)
• PKA: -2.25±0.20(Predicted)
• CAS DataBase Reference: 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propane-1-sulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propane-1-sulfonyl chloride(62605-69-0)
• EPA Substance Registry System: 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propane-1-sulfonyl chloride(62605-69-0)

Safety Data

• Hazardous Substances Data: 62605-69-0(Hazardous Substances Data)

Upstream product

• 63344-93-4 S-(3-phthalimido-propyl)-isothiourea; acetate 
• 1074-82-4 potassium phtalimide 

Downstream Products

• 181510-13-4 {Benzyloxy-[3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propane-1-sulfonyl]-amino}-acetic acid tert-butyl ester 
• 181510-11-2 3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-propane-1-sulfonic acid benzyl-benzyloxy-amide 
• 181510-15-6 {Benzyloxy-[3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propane-1-sulfonyl]-amino}-acetic acid 
• 181510-09-8 3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-propane-1-sulfonic acid benzyloxy-methyl-amide 
• 181510-07-6 3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-propane-1-sulfonic acid benzyloxy-amide 

Relevant articles and documents

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Quinazolines and related heterocyclic compounds and their therapeutic use

A compound of the formula wherein X is CR1 or N; Y is CR3 or N; R1, R3, R4, R5 and R6 are independently H, F, Cl, Br, I, or a hydrocarbon group which optionally contains one or more heteroatoms; R7 is a heterocyclic group including one or more N atoms; R' is Rx or NRyRz wherein Rx, Ry and Rz are each H or the same or different groups, including cyclic groups formed by Ry and Rz with the N atom, of up to 20 C atoms and optionally including up to 3 further heteroatoms selected from N, O and S; or a pharmaceutically acceptable salt, ester or solvate thereof, has therapeutic utility.

PYRROLO[2, 3-B]PYRIDIN-4-YL-BENZENESULFONAMIDE COMPOUNDS AS IKK2 INHIBITORS

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