626234-75-1Relevant academic research and scientific papers
Synthesis of 5-acylindoles via regioselective acylation of 3-trifluoroacetylindole
Li, Jun,Li, Bogang,Chen, Xiaozhen,Zhang, Guolin
, p. 1447 - 1450 (2003)
5-Acylindoles were synthesized by regioselective acylation of 3-trifluoroacetylindole with acyl chloride under the catalysis of Lewis acids, followed by hydrolysis of trifluoroacetyl and decarboxylation. Polar solvents were beneficial to the acylation and most of the Lewis acids tested showed good catalytic activities.
