62644-14-8 Usage
Description
1-(3-Fluorophenyl)-3-methyl-2-thiourea, with the molecular formula C8H9FN2S, is an organofluorine compound featuring a thiourea functional group. It is extensively utilized in the realms of organic synthesis and medicinal chemistry, making it a significant compound for chemical synthesis and research.
Uses
Used in Pharmaceutical Industry:
1-(3-Fluorophenyl)-3-methyl-2-thiourea is used as a precursor in the synthesis of various pharmaceutical compounds due to its unique structural properties and reactivity.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(3-Fluorophenyl)-3-methyl-2-thiourea serves as a key intermediate for the creation of a wide array of organic molecules, leveraging its thiourea functional group for various reactions.
Used in Medicinal Chemistry:
1-(3-Fluorophenyl)-3-methyl-2-thiourea is used as a potential pharmacological agent for its antibacterial and antifungal activities, making it a promising candidate for the development of new drugs to combat infections.
Used in Metal Coordination Chemistry:
1-(3-FLUOROPHENYL)-3-METHYL-2-THIOUREA is also explored for its potential use as a ligand in metal coordination chemistry, where it can form complexes with metal ions, potentially leading to applications in catalysis, materials science, and other areas.
Check Digit Verification of cas no
The CAS Registry Mumber 62644-14-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,6,4 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 62644-14:
(7*6)+(6*2)+(5*6)+(4*4)+(3*4)+(2*1)+(1*4)=118
118 % 10 = 8
So 62644-14-8 is a valid CAS Registry Number.
62644-14-8Relevant articles and documents
Synthesis and biological evaluation of 3-benzyl-1-methyl- and 1-methyl-3-phenyl-isothioureas as potential inhibitors of iNOS
Paesano, Nicola,Marzocco, Stefania,Vicidomini, Caterina,Saturnino, Carmela,Autore, Giuseppina,De Martino, Giovanni,Sbardella, Gianluca
, p. 539 - 543 (2007/10/03)
Novel benzyl- and phenyl-isothioureidic derivatives have been synthesised and evaluated as inhibitors of nitric oxide synthesis, induced in lipopolysaccharide (LPS)-activated J774.A1 macrophage cell line. The most potent iNOS inhibitor resulting was 1-methyl-3-phenyl-S-methyl isothiourea 5l.
