6265-30-1

Basic information

• Product Name: 3a,4,7,7a-Tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione (3aalpha,4alpha,7alpha,7aalpha)-
• CAS NO: 6265-30-1
• Molecular Formula: C₉H₉NO₂
• Molecular Weight: 163.176
• Mol File: 6265-30-1.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 362.1°Cat760mmHg
• Flash Point: 177.1°C
• Density: 1.339g/cm³
• CAS DataBase Reference: 3a,4,7,7a-Tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione (3aalpha,4alpha,7alpha,7aalpha)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3a,4,7,7a-Tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione (3aalpha,4alpha,7alpha,7aalpha)-(6265-30-1)
• EPA Substance Registry System: 3a,4,7,7a-Tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione (3aalpha,4alpha,7alpha,7aalpha)-(6265-30-1)

Safety Data

• Hazardous Substances Data: 6265-30-1(Hazardous Substances Data)

Usage

General Description

3a,4,7,7a-Tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione (3aalpha,4alpha,7alpha,7aalpha)- is a chemical compound with the molecular formula C9H9NO2. It is a cyclic organic compound with a tetrahydro-1H-isoindole-1,3-dione structure. 3a,4,7,7a-Tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione (3aalpha,4alpha,7alpha,7aalpha)- is primarily used in pharmaceutical research and drug development, where it may have potential applications as a therapeutic agent due to its unique chemical structure. Additionally, it may also have uses in other industries, such as in the development of new materials or as a chemical intermediate in organic synthesis. Further research may reveal additional potential applications and benefits for this compound.

Upstream product

• 541-59-3 maleiimide 
• 542-92-7 cyclopenta-1,3-diene 
• 42867-30-1 Silver maleimide 
• 61800-55-3 endo-5-carbamoylbicyclo[2.2.1]hept-2-ene-endo-6-carboxylic acid 
• 129-64-6 3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride 

Downstream Products

• 78087-47-5 (1S,2R,6S,7R)-4-Benzenesulfonyl-4-aza-tricyclo[5.2.1.0^2,6]dec-8-ene 
• 78028-14-5 N-chloroacetyl-4-azatricyclo<5.2.1.0^2,6>dec-8-ene 
• 521301-31-5 N-(m-tolylcarbamoyl)-4-azatricyclo[5.2.1.0^2,6]dec-8-ene 
• 521301-28-0 N-(p-tolylsulfonyl)-4-azatricyclo[5.2.1.0^2,6]dec-8-ene 
• 936747-84-1 C₃₃H₃₂O₃N₂ 

Relevant articles and documents

-

-

Pyrrolidine synthesis on polystyrene supports: Development of a 'one-pot' dipolar cycloaddition strategy

Preparation of substituted pyrrolidines was achieved by solid-phase synthesis via a room temperature 1,3-dipolar cycloaddition of a silver-azomethine ylide, generated in situ, with a polymer-supported maleimide.

IBX-mediated oxidation of unactivated cyclic amines: application in highly diastereoselective oxidative Ugi-type and aza-Friedel-Crafts reactions

The first o-iodoxybenzoic acid (IBX) mediated oxidation of unactivated amines to imines is described. A range of meso-pyrrolidines were shown to be suitable substrates. The chemical space was further explored with one-pot oxidative Ugi-type and aza-Friedel-Crafts reactions, which proved to be highly diastereoselective.

Quinoline-functionalized norbornene for fluorescence recognition of metal ions

A quinoline-functionalized norbornene (1) and its homopolymer (P1) for metal ions recognition have been synthesized and characterized. In CH3CN solution, 1 exhibited fluorescence enhancement response toward Hg2+, Zn2+ and Cu2+, with Hg2+ resulting in a green emission at 465 nm, and Zn2+/Cu2+ increasing 1's original emission at 406 nm. NMR titrations and DFT calculations results indicated that 1 bound Hg2+ in an imidic acid tautomeric form of the amide quinoline receptor, while Zn2+ and Cu2+ were bound to 1 in an amide tautomeric form. In addition, owing to the strong imidic acid tautomeric binding mode of 1-Hg2+ complex, 1 can recognized Hg2+ from Zn2+/Cu2+ and other competitive metal ions. In contrast, the homopolymer P1, which was obtained by ring opening metathesis polymerization (ROMP) method, exhibited only fluorescence enhancement sensing to Hg2+ and Cu2+ in an amide tautomeric binding mode with increasing emission at 416 nm.