1609464-87-0Relevant articles and documents
Synthesis of new tandospirone analogues carrying 1-(3-(trifluoromethyl) phenyl)piperazine
Gunkara, Omer Tahir,Sucu, Bilgesu Onur,Guleli, Muge,Ocal, Nuket
, p. 1619 - 1628 (2014)
New tandospirone analogues containing a 1-[3-(trifluoromethyl)phenyl] piperazine (TFMPP) moiety have been synthesized by hydroarylation reactions with Pd(OAc)2. The perhydroisoindole derivatives were obtained by the reaction of reduced starting material with aryl-(heteroaryl) iodides under the same conditions. Spiro-1,3-indandionolylpyrrolidine derivatives having an array of stereocenters are reported.