62659-65-8

Upstream product

• 62659-67-0 7-bromo-5-(2-fluorophenyl)-1,3-dihydro-3-trifluoroacetoxy-2H-1,4-benzodiazepin-2-one 
• 10329-38-1 7-bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one 4-oxide 
• 1647-74-1 5-bromo-2-bromoacetamido-2'-fluorobenzophenone 
• 2647-50-9 7-bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one 

Downstream Products

• 62659-60-3 3-fluoro-7-bromo-5-(2-fluorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one 
• 62659-59-0 7-bromo-3-fluoro-5-(2-fluoro-phenyl)-1,3-dihydro-benzo[e][1,4]diazepin-2-one 

Relevant academic research and scientific papers

Asymmetric Transformation. II. Racemization Reaction of 1,4-Benzodiazepinooxazole Derivative

Optically active crystals of 10-bromo-11b-(2-fluorophenyl)-2,3,7,11b-tetrahydrooxazolo-benzodiazepin-6(5H)-one were obtained by preferential crystallization; they were sometimes levorotatory and sometimes dextrorotatory.This phenomenon was pro

3-FLUOROBENZODIAZEPINES

Benzodiazepines that bear a fluorine substituent in the metabolically active C-3 position were prepared by the reaction of diethylaminosulfur trifluoride (DAST) with the corresponding 3-hydroxybenzodiazepines.These products are surprisingly stable to hydrolysis and possess potent antianxiety and muscle-relaxing properties.