627099-30-3

Upstream product

• 3262-72-4 (S)-N-(tert-butoxycarbonyl)serine 
• 108149-63-9 4-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 
• 95715-86-9 (S)-2,2-dimethyl-oxazolidine-3,4-dicarboxylic acid 3-tert-butyl ester 4-methyl ester 
• 2766-43-0 N-tert-butyloxycarbonyl-L-serine methyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 627099-18-7 4-(3-formylphenoxymethyl)-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthesis of 3-Aminochroman Derivatives by Radical Cyclization

(Equation presented) Enantiomerically pure 5-acetyl-3-amino-3,4-dihydro-2H- 1-benzopyran and methyl 3-amino-3,4-dihydro-2H-1-benzopyran-5-carboxylate were successfully synthesized starting from D- or L-serine. The formation of the benzopyran ring involved a radical cyclization step. The enantiomeric purities of the final aminochroman derivatives were determined by capillary electrophoresis using β-cyclodextrins as a chiral selector.