62737-71-7

Usage

Uses

Used in Organic Synthesis:
2-[1-(2-FURYL)ETHYLIDENE]MALONONITRILE is used as a reagent in organic synthesis for its ability to form carbon-carbon bonds, making it a valuable component in the creation of various organic compounds.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2-[1-(2-FURYL)ETHYLIDENE]MALONONITRILE is used as a building block for the development of new drugs, leveraging its structural properties to enhance the synthesis of medicinal compounds.
Used in Agrochemical Development:
2-[1-(2-FURYL)ETHYLIDENE]MALONONITRILE is also utilized in the agrochemical sector as a key intermediate in the synthesis of various agrochemicals, contributing to the development of effective crop protection products.
Used in the Production of Fine Chemicals:
2-[1-(2-FURYL)ETHYLIDENE]MALONONITRILE is employed as a versatile component in the preparation of fine chemicals, which are essential in a wide range of applications, including fragrances, dyes, and other specialty chemicals.
Used in Organic Light-Emitting Diodes (OLEDs):
In the field of optoelectronics, 2-[1-(2-FURYL)ETHYLIDENE]MALONONITRILE has been studied for its potential use as a luminescent material in OLEDs, indicating its application in the development of advanced display and lighting technologies.

InChI:InChI=1/C9H6N2O/c1-7(8(5-10)6-11)9-3-2-4-12-9/h2-4H,1H3

Upstream product

• 1192-62-7 1-(2-furyl)-1-ethanone 
• 109-77-3 malononitrile 

Downstream Products

• 80733-25-1 2-Amino-6-(fur-2-yl)-4-methylthio-3-nitro-benzonitrile 
• 77198-57-3 1-amino-5-(2-furyl)-3-phenyl-2,6-benzenedicarbonitrile 
• 6017-21-6 benzeneazomalononitrile 
• 115802-03-4 2-amino-4-(furan-2-yl)-6-(thiophen-2-yl)isophthalonitrile 
• 102354-19-8 2-[(E)-3-(Ethyl-phenyl-amino)-1-furan-2-yl-allylidene]-malononitrile 
• 102354-22-3 2-[(E)-3-(Cyclohexyl-methyl-amino)-1-furan-2-yl-allylidene]-malononitrile 
• 102354-20-1 2-[(E)-3-(Butyl-phenyl-amino)-1-furan-2-yl-allylidene]-malononitrile 
• 102354-18-7 2-[(E)-1-Furan-2-yl-3-(methyl-phenyl-amino)-allylidene]-malononitrile 
• 328087-61-2 2-amino-4-(furan-2-yl)-6-(2-hydroxyphenyl)nicotinonitrile 
• 1620550-33-5 ethyl 2-cyano-3,5-di(furan-2-yl)benzoate 
• 1421534-73-7 2-amino-4-(furan-2-yl)-6-(5-methyl-thiophen-2-yl)isophthalonitrile 

Relevant academic research and scientific papers

Asymmetric organocatalytic vinylogous Michael addition triggered triple-cascade reactions of 2-hydroxycinnamaldehydes and vinylogous nucleophiles: construction of benzofused oxabicyclo[3.3.1]nonane scaffolds

An organocatalytic vinylogous Michael addition triggered triple-cascade reaction has been developed. 2-Hydroxycinnamaldehydes worked under iminium activation with either acyclic or cyclic ketone-derived α,α-dicyanoalkenes, yielding the benzofused oxabicyclo[3.3.1]nonanes bearing one quaternary stereocenter with excellent stereoselectivities.

A [5 + 1] annulation strategy for the synthesis of multifunctional biaryls and: P -teraryls from 1,6-Michael acceptor ketene dithioacetals

A new type of ketene dithioacetal, 2-(3,3-bis-methylsulfanyl-1-arylallylidene)malononitriles containing 1,4 and 1,6-Michael acceptors, were synthesized to study their reactivity for the synthesis of a new molecular entity. We report a [5 + 1] annulation s

Transition metal free synthesis of multifunctional thiomethylated-benzenes from aryl/heteroaryl/cyclopropyl methyl ketones

A base-promoted strategic synthesis of various functionalized thiomethylated-benzenes has been established from aryl/heteroaryl/cyclopropyl methyl ketone. We can directly access the thiomethylated-benzene nucleus embedded with diverse functional group by

"on Water" Direct Catalytic Vinylogous Aldol Reaction of Silyl Glyoxylates

The unique reactivity of water in the direct catalytic vinylogous aldol reaction of silyl glyoxylates is reported. With the hydrogen-bonding networks from water, the unfavorable homogeneous reactions in organic solvents were severely suppressed, and the "

A Simple and Clean Synthesis of Polysubstituted 2,6-Dicyanoanilines Catalyzed by KF/alumina

A simple and clean synthesis of polysubstituted 2,6-dicyanoanilines has been developed via the reaction of arylidenemalonodinitriles with 1-arylethylidenemalonodinitriles in ethanol catalyzed by KF/ alumina. Use of non-hazardous solid base as a catalyst,

Basic ionic liquid as catalyst for the efficient and green synthesis of 2-amino-3-nitrobenzonitriles in ethanol

A basic ionic liquid, [BmIm]OH was used as catalyst in the cyclocondensation of various kinds of vinylmalononitriles with nitroolefins in ethanol at reflux. A series of 2-amino-3-nitrobenzonitriles were obtained in reasonable yields. The straightforward and green protocol was found to be fairly efficient, and the catalyst could be recycled and reused in subsequent reactions with consistent activity. The mechanism of the reaction was discussed.

Nitriles in Organic Synthesis. The Chemical Behavior of - and malononitriles

The chemical behavior of - and malononitriles 1a and b toward electrophilic reagents, active methylene reagents and (arylmethylene)malononitriles is described.

Iminoformylation Reaction of Substituted Crotonnitriles. I. Synthesis of New N,N-Disubstituted 4-Amino-1,1-dicyanobuta-1,3-dienes

A usefull and efficient method for the synthesis of 4-amino-1,1-dicyanobuta-1,3-dienes 10-20 based on the iminoformylation reaction of crotonnitriles 7-9 with the system triethyl orthoformate/secondary amine in the presence of an acidic catalyst is described.This novel route to the title compounds yields products which are easy to isolate and to purify and also allows to prepare the hitherto unknown N-aryl substituted 4-amino-1,1-dicyanobuta-1,3-dienes.Hence it is advantageous as compared to existing iminoformylation reactions of crotonnitriles using formamide acetals.