627461-29-4

Upstream product

• 17763-71-2 4-carbomethoxyphenyl triflate 
• 627461-21-6 tert-Butyl-((1R,3aR,4S,7aR)-1-ethynyl-7a-methyl-octahydro-inden-4-yloxy)-dimethyl-silane 
• 627461-22-7 Trifluoro-methanesulfonic acid 1-[(1S,3aR,4S,7aS)-4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-vinyl ester 
• 140659-43-4 [1S-(1β,4β,7aβ)]-[1R-(3aα)]-octahydro-1-acetyl-4-[(tert-butyldimethylsilyl)oxy]-7a-methyl-1H-indene 

Downstream Products

• 627461-31-8 4-((1S,3aR,7aR)-7a-Methyl-4-oxo-octahydro-inden-1-ylethynyl)-benzoic acid methyl ester 
• 627461-35-2 4-{(1S,3aS,7aS)-7a-Methyl-4-[2-[(3S,5R)-2-methylene-3,5-bis-triisopropylsilanyloxy-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-octahydro-inden-1-ylethynyl}-benzoic acid methyl ester 

Relevant academic research and scientific papers

The First Locked Side-Chain Analogues of Calcitriol (1α,25- Dihydroxyvitamin D3) Induce Vitamin D Receptor Transcriptional Activity

(Equation presented) We describe the synthesis of the first locked side-chain analogues of the natural hormone 1α,25-(OH)2-D 3 and their effects on gene transcription in human colon cancer cells. Analogue 2 was more potent than 1α.25