627461-35-2Relevant academic research and scientific papers
The First Locked Side-Chain Analogues of Calcitriol (1α,25- Dihydroxyvitamin D3) Induce Vitamin D Receptor Transcriptional Activity
Perez-Garcia, Xenxo,Rumbo, Antonio,Larriba, Maria Jesus,Ordonez, Paloma,Munoz, Alberto,Mourino, Antonio
, p. 4033 - 4036 (2007/10/03)
(Equation presented) We describe the synthesis of the first locked side-chain analogues of the natural hormone 1α,25-(OH)2-D 3 and their effects on gene transcription in human colon cancer cells. Analogue 2 was more potent than 1α.25
