627503-55-3

Upstream product

• 627503-43-9 (S)-3,3-bis(2,4,6-trimethylphenylmethyl)-8,8-dimethyl-7-oxa-1-azabicyclo[3.3.0]octan-2-one 
• 4761-00-6 2,4,6-trimethylbenzylbromide 
• 98-59-9 p-toluenesulfonyl chloride 
• 627503-49-5 (S)-3,3-bis(2,4,6-trimethylphenylmethyl)-5-hydroxymethylpyrrolidin-2-one 
• 99208-71-6 (5S)-1-aza-2,2-dimethyl-3-oxa-8-oxo-bicyclo[3.3.0]octane 

Downstream Products

• 627503-60-0 (S)-5-((diphenylphosphino)methyl)-3,3-bis[1-(2,4,6-trimethylphenyl)methyl]pyrrolidin-2-one 

Relevant academic research and scientific papers

Asymmetric Alkylation of N-Toluenesulfonylimines with Dialkylzinc Reagents Catalyzed by Copper-Chiral Amidophosphine

The synthetic procedure of a chiral amidophosphine ligand 5 bearing two bulky substituents, 2,4,6-trimethylphenylmethyl or 2,4,6-triisopropylphenylmethyl groups, on the pyrrolidine ring was improved by employing the borane-THF reduction of the lactam-alco