6277-65-2 Usage
Uses
Used in Organic Synthesis:
(2-nitro-3-phenylcyclopropyl)(phenyl)methanone is used as a key intermediate in organic synthesis for the production of various complex organic molecules. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (2-nitro-3-phenylcyclopropyl)(phenyl)methanone is used as a starting material for the development of new drugs. Its potential as an antitumor agent has been noted, and ongoing research aims to explore its efficacy and safety in treating various types of cancer.
Used in Drug Development:
(2-nitro-3-phenylcyclopropyl)(phenyl)methanone is utilized in drug development to create novel pharmaceutical compounds with potential therapeutic applications. Its pharmacological properties are being studied to determine its suitability for treating specific diseases and conditions, with a focus on its antitumor capabilities.
Used in Pharmaceutical Industry:
(2-nitro-3-phenylcyclopropyl)(phenyl)methanone is used as a chemical building block in the pharmaceutical industry for the creation of innovative drugs. Its potential applications in cancer treatment and other therapeutic areas are being explored, with the aim of developing new medications that can improve patient outcomes and address unmet medical needs.
Check Digit Verification of cas no
The CAS Registry Mumber 6277-65-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,7 and 7 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6277-65:
(6*6)+(5*2)+(4*7)+(3*7)+(2*6)+(1*5)=112
112 % 10 = 2
So 6277-65-2 is a valid CAS Registry Number.
6277-65-2Relevant academic research and scientific papers
D/H Exchange in Nitro Diastereomers
Kingsbury, Charles A.
, p. 3838 - 3846 (2007/10/03)
The two diastereomers of 4-nitro-1,3-diphenylpentan-1-one behave differently in deuterium for hydrogen exchange in DMSO-d6/D2O solutions using various bases as catalyst. Reaction of the erythro diastereomer gives largely the same diastereomer upon D/H exchange (retention), i.e., exchange exceeds epimerization. Pyridine and acetonitrile as solvents lead to faster epimerization than exchange. In the threo diastereomer (DMSO-d6 solution), epimerization exceeds exchange, and the anion to some extent regains the same hydrogen originally removed by the base on the opposite face. 2-Bromo-4-nitro-1,3-diphenylbutan-1-one undergoes ring closure to the cyclopropane faster than exchange (within seconds). The cyclopropane shows faster exchange than equilibration, i.e., retention of configuration, although it is the hydrogen α to carbonyl that is involved.
Vicarious nucleophilic substitution of hydrogen in electrophilic alkenes
Makosza,Kwast
, p. 5001 - 5018 (2007/10/02)
Carbanions containing leaving groups react in the presence of base with electrophilic alkenes giving products in which vinylic hydrogen is replaced with the carbanion moiety. They are formed via addition - β-elimination pathway analogous to the vicarious
