62777-25-7

Basic information

• Product Name: L-2-AMINO-5-PHENYL-PENTANOIC ACID
• Synonyms: H-NVA(5-PHENYL)-OH;L-2-AMINO-5-PHENYL-PENTANOIC ACID;L-Nva(5-phenyl)-OH;L-PEA
• CAS NO: 62777-25-7
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.24
• Product Categories: Phenylalanine analogs and other aromatic alpha amino acids;Amino Acid Derivatives;a-amino
• Mol File: 62777-25-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 228-230 °C
• Boiling Point: 333.5 °C at 760 mmHg
• Flash Point: 155.5 °C
• Appearance: /
• Density: 1.128 g/cm³
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: Acetic Acid (Slightly, Heated, Sonicated), Aqueous Base (Slightly)
• PKA: 2.52±0.24(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: L-2-AMINO-5-PHENYL-PENTANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: L-2-AMINO-5-PHENYL-PENTANOIC ACID(62777-25-7)
• EPA Substance Registry System: L-2-AMINO-5-PHENYL-PENTANOIC ACID(62777-25-7)

Safety Data

• Hazardous Substances Data: 62777-25-7(Hazardous Substances Data)

Usage

General Description

L-2-AMINO-5-PHENYL-PENTANOIC ACID, also known as L-2-amino-5-phenylvaleric acid, is an organic compound with the chemical formula C11H15NO2. It is a non-proteinogenic amino acid, meaning it is not used in the biosynthesis of proteins. L-2-AMINO-5-PHENYL-PENTANOIC ACID is used as a chiral auxiliary in organic synthesis and as a building block for the synthesis of pharmaceuticals and other compounds. It has also been studied for its potential use in the treatment of neurological disorders and inflammatory diseases. L-2-AMINO-5-PHENYL-PENTANOIC ACID is a white solid at room temperature and is sparingly soluble in water.

Upstream product

• 52161-76-9 (E,2S)-2-amino-5-phenyl-pent-4-enoic acid 
• 52161-73-6 2-acetylamino-2-(3-phenyl-propyl)malonic acid diethyl ester 
• 81867-09-6 ethyl 2-oxo-5-phenylpentanoate 
• 637-59-2 1-Bromo-3-phenylpropane 
• 852298-85-2 (4S,5R)-1-((S)-2-Azido-5-phenyl-pentanoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 852298-77-2 (4S,5R)-1-((R)-2-Bromo-5-phenyl-pentanoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 852298-94-3 (S)-2-Azido-5-phenyl-pentanoic acid 
• 121704-10-7 2-(2-Methoxy-acetylamino)-5-phenyl-pentanoic acid 
• 88768-11-0 2-oxo-5-phenylpentanoic acid 
• 62732-55-2 2-Acetylamino-2-(3-phenyl-propyl)-malonic acid 

Downstream Products

• 873329-61-4 C₁₄H₂₃NO₂Si 
• 1352825-27-4 (S)-2-(5-methoxybenzofuran-2-carboxamido)-5-phenylpentanoic acid 
• 768366-81-0 (S)-2-(3-methyl-benzoylamino)-5-phenyl-pentanoic acid 
• 87053-93-8 Boc-ΔAla-L-Ala-L-Hmb-L-App-NH2 
• 87053-90-5 App-NH₂ hydrochloride 
• 120679-17-6 Boc-Ser(Bzl)-Ala-Hmb-App-ONSu 
• 120679-15-4 Boc-Ser(Bzl)-Ala-Hmb-App-OH 
• 56072-96-9 AM-toxin II 
• 400886-11-5 (S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-propionyloxy)-3-methyl-butyrylamino]-5-phenyl-pentanoic acid allyl ester 
• 400886-08-0 (S)-2-[(S)-2-((S)-2-Amino-propionyloxy)-3-methyl-butyrylamino]-5-phenyl-pentanoic acid allyl ester 
• 400886-12-6 (S)-2-Amino-5-phenyl-pentanoic acid allyl ester 
• 666719-11-5 (4-cyclohexyl-1-hydroxymethyl-butyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Synthesis method of multi-configuration long-chain phenyl amino acid compound

The invention relates to a method for synthesizing a multi-configuration long-chain phenyl amino acid compound. The method comprises the following steps: reacting a compound shown in a formula I witha compound shown in a formula II or an isomer thereof in

Controlling diastereoselectivity in the reactions of enantiomerically pure α-bromoacyl-imidazolidinones with nitrogen nucleophiles: Substitution reactions with retention or inversion of configuration

Diastereoselective substitution reactions of α-bromoacyl- imidazolidinones with nitrogen nucleophiles can be promoted with either retention or inversion of configuration by carrying out reactions under epimerising or non-epimerising conditions. The Royal Society of Chemistry 2005.

Enantioselective synthesis of (S)-amino acids by phenylalanine dehydrogenase from Bacillus sphaericus: use of natural and recombinant enzymes

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