98628-27-4Relevant articles and documents
Organocatalytic one-pot oxidative cleavage of terminal diols to dehomologated carboxylic acids
Shibuya, Masatoshi,Doi, Ryusuke,Shibuta, Takuro,Uesugi, Shun-Ichiro,Iwabuchi, Yoshiharu
, p. 5006 - 5009 (2013/01/15)
The organocatalytic one-pot oxidative cleavage of terminal 1,2-diols to one-carbon-unit-shorter carboxylic acids is described. The combination of 1-Me-AZADO (cat.), NaOCl (cat.), and NaClO2 caused smooth one-pot oxidative cleavage under mild conditions. A broad range of substrates including carbohydrates and N-protected amino diols were converted without epimerization. Terminal triols and tetraols respectively underwent cleavage of their C-2 and C-3 moieties to afford their corresponding two- and three-carbon-unit-shorter carboxylic acids.
Solid-phase synthesis of dehydropeptide, AM-toxin II, using a novel selenyl linker by side-chain tethered strategy
Horikawa, Eiji,Kodaka, Masato,Nakahara, Yoshiaki,Okuno, Hiroaki,Nakamura, Kazuhiko
, p. 8337 - 8339 (2007/10/03)
The cyclic dehydrodepsipeptide, AM-toxin II, was efficiently synthesized by a solid-phase method using a novel selenyl linker. The cleavage from the resin with formation of a double bond is successfully achieved under mild oxidative conditions with TBHP.