98628-27-4

Basic information

• Product Name: Boc-L-2-Amino-5-phenyl-pentanoic acid
• Synonyms: (S)-2-(tert-Butoxycarbonylamino)-5-phenylpentanoic acid;(S)-alpha-[[(1,1-Dimethylethoxy)carbonyl]amino]benzenepentanoic acid;Boc-(S)-2-Amino-5-phenyl-pentanoic acid;Boc-L-2-Amino-5-phenyl-pentanoic acid
• CAS NO: 98628-27-4
• Molecular Formula: C₁₆H₂₃NO₄
• Molecular Weight: 293.36
• Mol File: 98628-27-4.mol

Chemical Properties

• Boiling Point: 480.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.121
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.98±0.21(Predicted)
• CAS DataBase Reference: Boc-L-2-Amino-5-phenyl-pentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-L-2-Amino-5-phenyl-pentanoic acid(98628-27-4)
• EPA Substance Registry System: Boc-L-2-Amino-5-phenyl-pentanoic acid(98628-27-4)

Safety Data

• Hazardous Substances Data: 98628-27-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Boc-L-2-Amino-5-phenyl-pentanoic acid is used as a building block for the preparation of complex organic molecules and in the synthesis of peptides and pharmaceuticals. Its ability to protect amino acid residues during chemical reactions is crucial for the development of new drugs and therapeutic agents.
Used in Organic Chemistry:
In the field of organic chemistry, Boc-L-2-Amino-5-phenyl-pentanoic acid serves as an essential reagent for the synthesis of various organic compounds. Its unique structure allows for the creation of a wide range of molecules with potential applications in different industries.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 62777-25-7 (S)-2-amino-4-phenylvaleric acid 
• 1400695-56-8 C₁₂H₁₇N₃O₂ 
• 1400695-38-6 tert-butyl ((2R,3R)-1,2-dihydroxy-6-phenylhexan-3-yl)carbamate 

Downstream Products

• 1221877-32-2 (S)-2-(2-(1H-imidazol-5-yl)acetamido)-N-(4-phenoxyphenyl)-5-phenylpentanamide 
• 1222196-33-9 (S)-2-amino-N-(4-phenoxyphenyl)-5-phenylpentanamide 
• 400886-11-5 (S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-propionyloxy)-3-methyl-butyrylamino]-5-phenyl-pentanoic acid allyl ester 
• 400886-08-0 (S)-2-[(S)-2-((S)-2-Amino-propionyloxy)-3-methyl-butyrylamino]-5-phenyl-pentanoic acid allyl ester 
• 400886-12-6 (S)-2-Amino-5-phenyl-pentanoic acid allyl ester 
• 666719-11-5 (4-cyclohexyl-1-hydroxymethyl-butyl)-carbamic acid tert-butyl ester 
• 904324-81-8 {1-[5-(3-methyl-1H-indazol-5-yl)-pyridin-3-yloxymethyl]-4-phenyl-butyl}-carbamic acid tert-butyl ester 
• 904324-66-9 [1-(5-bromo-pyridin-3-yloxymethyl)-4-phenyl-butyl]-carbamic acid tert-butyl ester 
• 666718-84-9 (1-hydroxymethyl-4-phenyl-butyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Organocatalytic one-pot oxidative cleavage of terminal diols to dehomologated carboxylic acids

The organocatalytic one-pot oxidative cleavage of terminal 1,2-diols to one-carbon-unit-shorter carboxylic acids is described. The combination of 1-Me-AZADO (cat.), NaOCl (cat.), and NaClO2 caused smooth one-pot oxidative cleavage under mild conditions. A broad range of substrates including carbohydrates and N-protected amino diols were converted without epimerization. Terminal triols and tetraols respectively underwent cleavage of their C-2 and C-3 moieties to afford their corresponding two- and three-carbon-unit-shorter carboxylic acids.

Exploration of the P1 SAR of aldehyde cathepsin K inhibitors.

The synthesis and biological activity of a series of aldehyde inhibitors of cathepsin K are reported. Exploration of the properties of the S(1) subsite with a series of alpha-amino aldehyde derivatives substituted at the P(1) position afforded compounds with cathepsin K IC(50)s between 52 microM and 15 nM.

Solid-phase synthesis of dehydropeptide, AM-toxin II, using a novel selenyl linker by side-chain tethered strategy

The cyclic dehydrodepsipeptide, AM-toxin II, was efficiently synthesized by a solid-phase method using a novel selenyl linker. The cleavage from the resin with formation of a double bond is successfully achieved under mild oxidative conditions with TBHP.