627812-08-2

Basic information

• Product Name: 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-4-methylsulfanyl-1,2-dihydropyrimidin-2-thione
• Synonyms: 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-4-methylsulfanyl-1,2-dihydropyrimidin-2-thione
• CAS NO: 627812-08-2
• Molecular Weight: 602.689
• Mol File: 627812-08-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-4-methylsulfanyl-1,2-dihydropyrimidin-2-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-4-methylsulfanyl-1,2-dihydropyrimidin-2-thione(627812-08-2)
• EPA Substance Registry System: 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-4-methylsulfanyl-1,2-dihydropyrimidin-2-thione(627812-08-2)

Safety Data

• Hazardous Substances Data: 627812-08-2(Hazardous Substances Data)

Upstream product

• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 
• 22860-91-9 2,3,5-tri-O-benzoyl-D-ribofuranosyl bromide 
• 58214-53-2 2,3,5-tri-O-benzoyl-β-D-ribofuranosyl isothiocyanate 

Downstream Products

• 13233-20-0 2-thiocytidine 

Relevant articles and documents

An Efficient Route to Pyrimidine Nucleoside Analogues by [4 + 2] Cycloaddition Reaction

We report here an efficient synthesis for pyrimidine nucleoside analogues by [4 + 2] cycloaddition reaction. These compounds were obtained by convergent chemistry from glycosyl isothiocyanates 3a-f (pyranoses, furanoses, and dissaccharides) and diazadienium salt 5. In fact, diazapentadienium iodide 5 prepared from vinylthioamide 4 is an efficient intermediate in heterocyclic synthesis and reacts with isothiocyanates 3a-f affording β-D-uracil analogues 7a-f in good yields and with total regiocontrol. All compounds were fully characterized by IR, HRMS, and 13C and 1H NMR (COSY and HMQC).