22860-91-9

Basic information

• Product Name: 2,3,5-tri-O-benzoyl-D-ribofuranosyl bromide
• Synonyms: 2,3,5-tri-O-benzoyl-D-ribofuranosyl bromide
• CAS NO: 22860-91-9
• Molecular Weight: 525.353
• Mol File: 22860-91-9.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: 2,3,5-tri-O-benzoyl-D-ribofuranosyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,5-tri-O-benzoyl-D-ribofuranosyl bromide(22860-91-9)
• EPA Substance Registry System: 2,3,5-tri-O-benzoyl-D-ribofuranosyl bromide(22860-91-9)

Safety Data

• Hazardous Substances Data: 22860-91-9(Hazardous Substances Data)

Upstream product

• 115459-50-2 2,3,5-Tri-O-benzoyl-D-ribofuranose 
• 98-88-4 benzoyl chloride 
• 52783-53-6 methyl 2,3,3'-tri-O-benzoyl-β-D-apiofuranoside 
• 69350-76-1 methyl 2,3,5-tri-O-benzoyl-αβ-D-ribofuranoside 
• 532-20-7 D-Ribose 
• 1824-96-0 methyl ribofuranoside 
• 22224-41-5 1,3,5-tri-O-benzoyl-α-D-ribofuranoside 
• 14215-97-5 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose 
• 69339-86-2 1,2,3,5-tetra-O-benzoyl-α-D-ribofuranoside 
• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 

Downstream Products

• 18784-01-5 N¹-(2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl)-3-aminocarbonylpyridinium bromide 
• 49555-41-1 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)hexahydropyrimidin-2-one 
• 77249-70-8 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)tetrahydro-2H-1,3-diazepine-2-one 
• 75043-10-6 1,2-O--α-D-ribofuranose 
• 75043-09-3 1,2-O-<6-nitroindol-1-yl(phenyl)methylidene>-α-D-ribofuranose 
• 75043-14-0 Acetic acid (3aR,5R,6R,6aR)-5-acetoxymethyl-2-(6-nitro-indol-1-yl)-2-phenyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester 
• 75043-11-7 5-O-benzoyl-1,2-O-<6-nitroindol-3-yl(phenyl)methylidene>-α-D-ribofuranose 
• 66981-58-6 3,5-di-O-benzoyl-α-D-ribofuranoside-prop-2-ynyl-1,2-orthobenzoate 
• 1431370-46-5 pent-4-enyl 2-O-benzoyl-3,5-di-O-benzyl-β-D-ribofuranoside 
• 1431370-48-7 methyl 2,3,4-tri-O-benzyl-6-O-(2-O-benzoyl-3,5-di-O-benzyl-β-D-ribofuranosyl)-α-D-glucopyranoside 
• 1431370-49-8 tert-butyl 2-O-benzoyl-3,5-di-O-benzyl-β-D-ribofuranoside 
• 1431370-50-1 pent-4-enyl 2,3-di-O-benzyl-5-O-(2-O-benzoyl-3,5-di-O-benzyl-β-D-ribofuranosyl)-α-D-arabinofuranoside 
• 1431370-51-2 pent-4-enyl 3,5-di-O-benzyl-β-D-ribofuranoside 
• 1431370-53-4 methyl 2,3,4-tri-O-benzyl-6-O-(3,5-di-O-benzyl-β-D-ribofuranosyl)-α-D-glucopyranoside 

Relevant articles and documents

Substituted pyrazole compound, preparation method, pharmaceutical composition and applications thereof

The invention discloses a substituted pyrazole compound represented by a formula I, and a preparation method, a pharmaceutical composition and applications thereof, wherein the compound has characteristics of good stability, excellent solubility, low cytotoxicity and remarkable neuroprotective effect, can effectively prevent and treat nerve cell injury, and is an ideal medicinal compound for preventing or treating cerebral stroke, cerebral embolism, cerebral stroke sequelae, cerebral stroke dyskinesia, mitochondrial encephalomyopathy and amyotrophic lateral sclerosis of spinal cord.

Magnesium pyrophosphates in enzyme mimics of nucleotide synthases and kinases and in their prebiotic chemistry

Derivatives of ribosyl pyrophosphate have been synthesized, and examined with magnesium salts in the coupling of the ribose unit to various nucleophiles, including pyrazole and 2-chloroimidazole. Only with the magnesium salt present did they generate the ribosyl cation by binding to the leaving group and then couple the ribose derivative with nucleophiles. The role of magnesium salts in phosphorylation of methanol by ATP was also examined. Here a remarkable effect was seen: phosphorylation by ATP was slowed with low concentrations of Mg2+ but accelerated by higher concentrations. Related effects were also seen in the effect of Mg2+ on phosphorylation by ADP. The likely mechanisms explain these effects.

Facile synthesis of β- And α-arabinofuranosides and application to cell wall motifs of M. tuberculosis

Propargyl 1,2-orthoesters of arabinose are exploited for the synthesis of 1,2-trans furanosides; easily accessible 1,2-trans ribofuranosides are converted to challenging 1,2-cis-arabinofuranosides by oxidoreduction. Utility of these protocols was demonstrated by the successful synthesis of major structural motifs present in the cell surface of Mycobacterium tuberculosis. Key furanosylations were carried out under gold-catalyzed glycosidation conditions.