62784-66-1

Basic information

• Product Name: Di-1-naphthylmethanol
• Synonyms: Di-1-naphthylmethanol;Bis(alpha-naphthyl)methanol
• CAS NO: 62784-66-1
• Molecular Formula: C₂₁H₁₆O
• Molecular Weight: 284.35
• Mol File: 62784-66-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 148 °C
• Boiling Point: 504.1°C at 760 mmHg
• Flash Point: 211.1°C
• Appearance: /
• Density: 1.208g/cm³
• Vapor Pressure: 5.55E-11mmHg at 25°C
• Refractive Index: 1.718
• Solubility: soluble in Toluene
• PKA: 13.28±0.20(Predicted)
• CAS DataBase Reference: Di-1-naphthylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: Di-1-naphthylmethanol(62784-66-1)
• EPA Substance Registry System: Di-1-naphthylmethanol(62784-66-1)

Safety Data

• Hazardous Substances Data: 62784-66-1(Hazardous Substances Data)

Usage

General Description

Di-1-naphthylmethanol is a chemical compound with the molecular formula C20H16O. It is also known as 1-naphthylmethanol or α-naphthylmethyl alcohol. This white crystalline solid is insoluble in water but soluble in organic solvents. Di-1-naphthylmethanol is used in the manufacture of organic chemicals, pharmaceuticals, and agrochemicals. It is also utilized as a reagent in organic synthesis and as a chiral auxiliary in asymmetric synthesis. Furthermore, it has been studied for its potential biological activities, including antioxidant and anti-inflammatory properties. Overall, di-1-naphthylmethanol is an important chemical compound with various industrial and research applications.

InChI:InChI=1/C21H16O/c22-21(19-13-5-9-15-7-1-3-11-17(15)19)20-14-6-10-16-8-2-4-12-18(16)20/h1-14,21-22H

Upstream product

• 1213744-28-5 (S)-di-(1-naphthyl)methyl α-(phenylthio)propanoate 

Downstream Products

• 607-50-1 1,1'-dinaphthylmethane 
• 605-78-7 bis(naphthalen-1-yl)methanone 
• 1312997-39-9 C₃₁H₂₆O₃S 
• 1187669-93-7 PhCO₂CH(1-Np)2 
• 1312997-43-5 C₃₂H₃₆O₂S 
• 1213744-28-5 (S)-di-(1-naphthyl)methyl α-(phenylthio)propanoate 
• 1312997-51-5 di(1-naphthyl)methyl (R)-α-(phenylthio)propanoate 
• 146300-52-9 (R)-α-(phenylthio)propanoic acid 
• 1214913-68-4 (S)-α-(phenylthio)propanoic acid 
• 1312997-38-8 C₃₁H₂₆O₂S 
• 1312997-45-7 C₃₃H₃₀O₂S 
• 1312997-46-8 C₃₂H₂₈O₂S 
• 1312997-40-2 C₃₀H₂₃ClO₂S 
• 1312997-42-4 C₃₁H₂₆O₂S 

Relevant articles and documents

METHOD FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID ESTER

Provided is a method for producing an optically active carboxylic acid ester at a high yield and with high enantioselectivity using dynamic kinetic resolution, said optically active carboxylic acid ester having an α-nitrogen substituent. This method for producing an optically active carboxylic acid ester includes a step in which racemic carboxylic acid represented by formula (a) and a specific alcohol or phenol derivative are reacted in a polar solvent having a dipole moment of at least 3.5 in the presence of an acid anhydride and an asymmetric catalyst, one enantiomer of the racemic carboxylic acid is selectively esterified, and the other enantiomer is racemized. In formula (a), Ra1 represents a nitrogen-containing heteroaromatic ring group bonded to an assymetric carbon via a nitrogen atom constituting a ring, and Ra2 is an organic group.

Kinetic resolution of α-substituted alkanoic acids promoted by homobenzotetramisole

A new method for catalytic nonenzymatic kinetic resolution of α-substituted alkanoic acids has been developed, which relies on their activation with DCC followed by enantioselective alcoholysis of the intermediate symm-anhydrides in the presence of the amidine-based catalyst homobenzotetramisole (HBTM). Moderate to excellent selectivity factors (s=5-96) have been obtained in the case of several classes of substrates, namely, α-aryl-, α-aryloxy/alkoxy-, α-halo-, α-azido-, and α-phthalimido-alkanoic acids. Under similar conditions, α-(arylthio/alkylthio)-alkanoic acids undergo dynamic kinetic resolution providing corresponding esters in up to 92 % ee and up to 93 % yield. Copyright