62796-78-5

Basic information

• Product Name: 1-(5,7-DINITRO-2,3-DIHYDRO-1H-INDOL-1-YL)ETHAN-1-ONE
• Synonyms: 1-(5,7-DINITRO-2,3-DIHYDRO-1H-INDOL-1-YL)ETHAN-1-ONE;1-Acetyl-5,7-dinitroindoline
• CAS NO: 62796-78-5
• Molecular Formula: C₁₀H₉N₃O₅
• Molecular Weight: 251.2
• Mol File: 62796-78-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 217-218 °C
• Boiling Point: 512.3±50.0 °C(Predicted)
• Appearance: /
• Density: 1.526±0.06 g/cm3(Predicted)
• PKA: -6.43±0.20(Predicted)
• CAS DataBase Reference: 1-(5,7-DINITRO-2,3-DIHYDRO-1H-INDOL-1-YL)ETHAN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5,7-DINITRO-2,3-DIHYDRO-1H-INDOL-1-YL)ETHAN-1-ONE(62796-78-5)
• EPA Substance Registry System: 1-(5,7-DINITRO-2,3-DIHYDRO-1H-INDOL-1-YL)ETHAN-1-ONE(62796-78-5)

Safety Data

• Hazardous Substances Data: 62796-78-5(Hazardous Substances Data)

Upstream product

• 496-15-1 1-indoline 
• 67932-53-0 5,7-dinitroindoline 
• 75-36-5 acetyl chloride 
• 16078-30-1 1-Acetyl-2,3-dihydro-1H-indole 

Downstream Products

• 511244-40-9 N-benzyloxycarbonyl-5,7-dinitroindoline 
• 36065-27-7 N-α-phenylethylacetamide 
• 692-33-1 N-allylacetamide 
• 1696-20-4 4-acetylmorpholine 
• 618-42-8 1-piperidin-1-yl-ethanone 
• 140-11-4 Benzyl acetate 
• 34904-91-1 1-(3,5-dimethoxyphenyl)-2-oxo-2-phenylethyl acetate 
• 21040-45-9 Cinnamyl acetate 
• 93-92-5 1-phenylethyl acetate 
• 5240-32-4 1-acetoxy-1-ethynyl cyclohexane 
• 105-87-3 3,7-dimethyl-2E,6-octadien-1-yl acetate 
• 115-95-7 linalool acetate 
• 622-45-7 cyclohexyl acetate 
• 62398-10-1 2-acetoxy-2-phenylacetophenone 

Relevant articles and documents

Photochemical protection of amines with Cbz and Fmoc groups

The photochemical conversion of amines into carbamates was achieved using N-Cbz-, N-Fmoc-, and N-Boc-5,7-dinitroindolines. This reaction allows the protection of amines in neutral medium. Primary and unhindered secondary amines were protected to yield their benzyloxycarbonyl- and 9-fluorenylmethoxycarbonyl derivatives efficiently, whereas bulky amines or anilines gave low yields or no product. On the other hand, the formation of N-Boc compounds, although possible, proceeded only with low yields.

Improved preparation of some nitroindolines

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