62802-43-1

Usage

Uses

Used in Pharmaceutical Industry:
2-CHLORO-N,N-DIMETHYLPYRIMIDIN-5-AMINE is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a building block for the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 2-CHLORO-N,N-DIMETHYLPYRIMIDIN-5-AMINE serves as an essential intermediate for the production of pesticides. Its incorporation into these chemical products aids in the development of effective and targeted pest control solutions.
Used as a Reagent in Organic Chemistry:
2-CHLORO-N,N-DIMETHYLPYRIMIDIN-5-AMINE is also utilized as a reagent in organic chemistry reactions, particularly for the formation of heterocyclic compounds. Its presence in these reactions facilitates the synthesis of complex organic molecules, broadening the scope of chemical research and applications.

Upstream product

• 56621-90-0 2-chloro-5-aminopyrimidine 
• 50-00-0 formaldehyd 

Relevant academic research and scientific papers

Substituent Effects on Exchange Coupling and Magnetic Relaxation in 2,2′-Bipyrimidine Radical-Bridged Dilanthanide Complexes

Systematic analysis of related compounds is crucial to the design of single-molecule magnets with improved properties, yet such studies on multinuclear lanthanide complexes with strong magnetic coupling remain rare. Herein, we present the synthesis and magnetic characterization of the series of radical-bridged dilanthanide complex salts [(Cp*2Ln)2(μ-5,5′-R2bpym)](BPh4) (Ln = Gd, Dy; R = NMe2 (1), OEt (2), Me (3), F (4); bpym = 2,2′-bipyrimidine). Modification of the substituent on the bridging 5,5′-R2bpym radical anion allows the magnetic exchange coupling constant, JGd-rad, for the gadolinium compounds in this series to be tuned over a range from -2.7 cm-1 (1) to -11.1 cm-1 (4), with electron-withdrawing or -donating substituents increasing or decreasing the strength of exchange coupling, respectively. Modulation of the exchange coupling interaction has a significant impact on the magnetic relaxation dynamics of the single-molecule magnets 1-Dy through 4-Dy, where stronger JGd-rad for the corresponding Gd3+ compounds is associated with larger thermal barriers to magnetic relaxation (Ueff), open magnetic hysteresis at higher temperatures, and slower magnetic relaxation rates for through-barrier processes. Further, we derive an empirical linear correlation between the experimental Ueff values for 1-Dy through 4-Dy and the magnitude of JGd-rad for the corresponding gadolinium derivatives that provides insight into the electronic structure of these complexes. This simple model applies to other organic radical-bridged dysprosium complexes in the literature, and it establishes clear design criteria for increasing magnetic operating temperatures in radical-bridged molecules.