62819-24-3

Basic information

• Product Name: methyl 5-deoxy-2,3-O-(1-methylethylidene)-5-triaza-1,2-dien-2-ium-1-ylpentofuranoside
• CAS NO: 62819-24-3
• Molecular Formula: C₉H₁₅N₃O₄
• Molecular Weight: 230.2405
• Mol File: 62819-24-3.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: methyl 5-deoxy-2,3-O-(1-methylethylidene)-5-triaza-1,2-dien-2-ium-1-ylpentofuranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-deoxy-2,3-O-(1-methylethylidene)-5-triaza-1,2-dien-2-ium-1-ylpentofuranoside(62819-24-3)
• EPA Substance Registry System: methyl 5-deoxy-2,3-O-(1-methylethylidene)-5-triaza-1,2-dien-2-ium-1-ylpentofuranoside(62819-24-3)

Safety Data

• Hazardous Substances Data: 62819-24-3(Hazardous Substances Data)

Upstream product

• 4099-85-8 ((3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol 
• 532-20-7 D-Ribose 
• 50-69-1 D-ribose 
• 36468-53-8 β-D-ribofuranose 
• 10257-32-6 D-ribose 
• 50610-99-6 1-O-methyl-2,3-O-isopropylidene-5-O-(methanesulfonyl)-β-D-ribofuranoside 
• 4137-56-8 methyl 2,3-O-isopropylidene-5-O-p-tolylsulfonyl-β-D-ribofuranoside 

Downstream Products

• 136933-97-6 ((3aR,4R,6R,6aR)-6-Methoxy-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl)-carbamic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 1033538-11-2 4-benzyl-1-(methyl 5-deoxy-2,3-O-isopropylidene-β-D-ribofuranosid-5-yl)-1H-1,2,3-triazole 
• 1197884-61-9 tert-butyl 3-(2-{1-[(6-methoxy-2,2-dimethyltetrahydrofuro-[3,4-d][1,3]dioxol-4-yl)methyl]-1H-1,2,3-triazol-4-yl}-1-[(4-methylphenyl)sulfonyl]ethyl)-1H-indole-1-carboxylate 
• 1217586-72-5 1-O-methyl-2,3-O-isopropylidene-5-(4-cyclohexene-1H-1,2,3-triazol-1-yl)-β-D-ribofuranose 
• 1217587-54-6 1-O-methyl-2,3-O-isopropylidene-5-[4-(1-hydroxycyclohexyl)-1H-1,2,3-triazol-1-yl]-β-D-ribofuranose 
• 1352299-43-4 3-tert-butyl-5-(4-fluorophenyl)-1-(((4R,6R)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl)imidazolidine-2,4-dione 
• 1259392-00-1 C₃₂H₄₃F₆N₃O₈ 
• 1259392-02-3 C₄₀H₅₀F₆N₄O₁₁ 
• 1259391-78-0 C₄₀H₅₀F₆N₄O₁₁ 
• 1428967-02-5 C₃₀H₄₅N₃O₁₀ 
• 1428967-54-7 C₃₀H₄₅N₃O₁₀ 
• 1428967-03-6 C₃₂H₄₉N₃O₁₀ 
• 1428967-55-8 C₃₂H₄₉N₃O₁₀ 
• 1259391-74-6 C₂₉H₃₉F₆N₃O₈ 

Relevant articles and documents

ACETONIDES OF α-HYDROXY-δ-ALTRONOLACTONES

The preparation and characterisation of some derivatives of α-hydroxy-δ-lactones, in which the δ-carbon substituent on the lactone ring is trans to an adjacent isopropylidene protected diol, are described; the X-ray crystal structures of 3,4-O-isopropylidene-D-altrono-1,5-lactone and of 3,4:6,7-di-O-isopropylidene-D-glycero-Daltro-heptono-1,5-lactone are reported.

New glycosylated platinum(II) phthalocyanine containing ribose moiety – synthesis and photophysical properties

The synthesis and spectral characterisation of new glycoconjugated phthalonitrile connected with triazole linker via Cu(II)-mediated click reaction is reported. Treatment of azido derivative of 1-methoxy-2,3- O-isopropylidene-β-D-ribose with 4-O-propargyloxy-substituted phthalonitrile in presence copper(II) sulfate pentahydrate and sodium L-ascorbate in tert-butanol/water gave desired glycophthalonitrile with 84% yield. This precursor underwent mixed-cyclisation with the tert-butyl-substituted phthalonitrile, to afford the mono-glycosylated A3B-type platinum(II) phthalocyanine. Upon irradiation this compound could sensitise the formation of singlet oxygen in acetone, with 0.95 quantum yield by comparative method with use of 1,3-diphenylisobenzofuran (DPBF) as scavenger.

Synthesis of a new class of naphthoquinone glycoconjugates and evaluation of their potential as antitumoral agents

A novel series of carbohydrate-based naphthoquinones was synthesized and evaluated for cytotoxicity against different cancer cell lines. The compounds derived from 5-hydroxy-1,4-naphthoquinone (juglone) showed better cytotoxicity profiles against HCT-116, A-549 and MDA-MB 435 human cancer cells than the parent compound. The results suggest that the hydroxyl group on the aromatic ring increased the pro-oxidant activity of these new naphthoquinone derivatives. Furthermore, two derivatives were found to be more active against melanoma cells (MDA-MB435) than the clinically useful anticancer agent doxorubicin, and none of the compounds caused mouse erythrocyte lysis.