628316-36-9Relevant academic research and scientific papers
Total Synthesis of Macroviracin D (BA-2836-4)
Mlynarski, Jacek,Ruiz-Caro, Juliana,Fuerstner, Alois
, p. 2214 - 2222 (2007/10/03)
The first total synthesis of the complex glycolipid macroviracin D (BA-2836-4) (1) is described. This antivirally active metabolite isolated from the mycelium extracts of Streptomyces sp. BA-2836 incorporates a unique 46-membered macrodilactone motif deco
Structure Assignment, Total Synthesis, and Antiviral Evaluation of Cycloviracin B1
Fuerstner, Alois,Albert, Martin,Mlynarski, Jacek,Matheu, Maribel,DeClercq, Erik
, p. 13132 - 13142 (2007/10/03)
The first total synthesis of the antivirally active glycolipid cycloviracin B1 (1) is described. The approach is based on a two-directional synthesis strategy which constructs the C 2-symmetrical macrodiolide core of the target by an
