62833-11-8

Upstream product

• 14062-19-2 p-tolylacetic acid ethyl ester 
• 109-94-4 formic acid ethyl ester 
• 623-73-4 diazoacetic acid ethyl ester 
• 104-87-0 4-methyl-benzaldehyde 

Downstream Products

• 91632-29-0 4-p-Tolyl-2H-isoxazol-5-one 
• 91632-43-8 2,5-di-p-tolyl-6H-1,3-oxazin-6-one 
• 91632-50-7 (Z)-3-(4-Methyl-benzoylamino)-2-p-tolyl-acrylic acid 
• 91632-55-2 (Z)-3-{[1-Cyano-1-p-tolyl-meth-(Z)-ylidene]-amino}-2-p-tolyl-acrylic acid 
• 91632-61-0 (Z)-3-{[1-Cyano-1-p-tolyl-meth-(Z)-ylidene]-amino}-2-p-tolyl-acrylic acid methyl ester 
• 91632-37-0 4,4'-Di-p-tolyl-4'H-[2,4']biisoxazolyl-5,5'-dione 
• 128839-68-9 2-(4-methylphenyl)propenoic acid ethyl ester 
• 78926-01-9 2-(4-methylphenyl)propanoic acid ethyl ester 
• 938-94-3 (R,S)-2-(4'-methylphenyl) propionic acid 

Relevant academic research and scientific papers

Synthesis of vinyl and electron-deficient aryl trifluoromethyl sulfides via Csp2?OH bond activation with AgSCF3 and n-Bu4NI/KI

Direct dehydroxytrifluoromethylthiolation of enols and electron-deficient phenols with AgSCF3 in the presence of n-Bu4NI and KI is reported, affording a series of vinyl and aryl trifluoromethyl sulfides in moderate to excellent yields. This work represents a rare example of direct functionalization of Csp2?OH bonds.

Br?nsted acid mediated cyclizations of ortho-aryl(ethynyl)pyrimidines

A high-yielding procedure for the synthesis of 5-aryl-4-(arylethynyl)pyrimidines from easily available 2-aryl-3-hydroxyacrylates is reported. These pyrimidines readily undergo cyclization in strong Br?nsted acids and, depending on the substitution in alky

Synthesis and anticancer evaluation of 3-substituted quinolin-4-ones and 2,3-dihydroquinolin-4-ones

A series of 3-aryl-5,7-dimethoxyquinolin-4-ones 8 and 3-aryl-5,7-dimethoxy- 2,3-dihydroquinolin-4-ones 13 were synthesized in good yields. Demethylation under a range of conditions afforded the corresponding 5-hydroxy and 5,7-dihydroxy derivatives. Biolog

Unusual anion effects in the iron-catalyzed formation of 3-hydroxyacrylates from aromatic aldehydes and ethyl diazoacetate

Due to the lability of one of the CO ligands in irans-[Fe(PNP)(CO) 2Cl]+ this compound is an efficient catalyst for the coupling of a series of aromatic aldehydes with ethyl diazoacetate (EDA), which give, in most cases, selectively 3-hydroxyacrylates rather than β-oxo esters. This reaction is strongly dependent on the nature of the counterion, Whereas with BF4- the reaction proceeds with conversions up to 90%, in the case of the counterions NO3-, CF 3COO-, CF3SO3-, SbF 6-, and BAr'4- [Ar' = 3,5-(CF 3)2C6H3] no reaction took place. In the case of PF6- only up to 20% conversion was achieved. A conceivable mechanism for the coupling of aromatic aldehydes with EDA was established by means of DFT/B3LYP calculations, which allowed the rationalization of both the chemoselectivity and the role of the counterions.