62849-46-1Relevant academic research and scientific papers
“One pot” synthesis of tertiary amines: Ru(II) catalyzed direct reductive N-benzylation of imines with benzyl bromide derivatives
Li, Bin,Yu, Jinghao,Li, Caihua,Li, Yibiao,Luo, Jianli,Shao, Yan
supporting information, p. 137 - 141 (2016/12/26)
The direct reductive N-benzylation of imines by reaction with benzyl bromide derivatives, in the presence of [RuCl2(p-cymene)]2catalyst and PhSiH3, is performed under mild conditions without additional base. This reaction proceeds by a tandem imine hydrosilylation/nucleophilic substitution with benzyl bromide derivatives to result the tertiary amines.
Copper-catalyzed N- and O-alkylation of amines and phenols using alkylborane reagents
Sueki, Shunsuke,Kuninobu, Yoichiro
supporting information, p. 1544 - 1547 (2013/06/26)
By the reaction of amines with alkylborane reagents in the presence of a catalytic amount of copper(II) acetate Cu(OAc)2 and di-tert-butyl peroxide, a cross-coupling reaction proceeded and alkylated amines were obtained in good to excellent yields. Phenols are also applicable for this reaction, and the corresponding alkyl aryl ethers were produced.
