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2-(3-fluorophenyl)-1,5-dimethyl-1,2-dihydro-3H-pyrazol-3-one is a complex organic compound with the molecular formula C11H11FN2O2. It is a derivative of pyrazolone, a heterocyclic compound with a pyrazole ring fused to a ketone group. This specific compound features a fluorophenyl group at the 2-position and two methyl groups at the 1-position, with the entire structure being part of a 1,2-dihydro-3H-pyrazol-3-one system. It is synthesized for various applications, including pharmaceuticals and agrochemicals, due to its potential biological activities. The presence of the fluorine atom can significantly influence the compound's reactivity and physical properties, making it a subject of interest in medicinal chemistry for the development of new drugs.

6286-80-2

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6286-80-2 Usage

Classification

Nonsteroidal anti-inflammatory drug (NSAID).

Primary use

To reduce pain and inflammation in conditions such as arthritis.

Mechanism of action

Inhibits the production of prostaglandins, which are chemicals in the body that cause pain and inflammation.

Potential applications

Antiproliferative and cytotoxic effects on various cancer cell lines, making it a potential candidate for cancer treatment.

Additional research

Studied for its potential use in treating neurological disorders such as Alzheimer's disease and Parkinson's disease.

Side effects

Associated with gastrointestinal irritation.

Precaution

Should be used with caution and under the supervision of a healthcare professional.

Check Digit Verification of cas no

The CAS Registry Mumber 6286-80-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,8 and 6 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6286-80:
(6*6)+(5*2)+(4*8)+(3*6)+(2*8)+(1*0)=112
112 % 10 = 2
So 6286-80-2 is a valid CAS Registry Number.

6286-80-2Downstream Products

6286-80-2Relevant academic research and scientific papers

Pyrazolone methylamino piperidine derivatives as novel CCR3 antagonists

Pegurier, Cecile,Collart, Philippe,Danhaive, Pierre,Defays, Sabine,Gillard, Michel,Gilson, Frederic,Kogej, Thierry,Pasau, Patrick,Van Houtvin, Nathalie,Van Thuyne, Marc,van Keulen, BerendJan

, p. 4228 - 4231 (2008/02/09)

The discovery and optimization of a novel class of potent CCR3 antagonists is described. Details of synthesis and SAR are given together with some ADME properties of selected compounds. An optimal balance between activities, physicochemical properties, and in vitro metabolic stability was reached by the proper choice of substituents.

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