62860-06-4Relevant academic research and scientific papers
LC-NMR and LC-MS analysis of 2,3,10,11-oxygenated protoberberine metabolites in Corydalis cell cultures
Isawa, Kinuko,Kuribayashi, Ayako,Sugiura, Makiko,Moriyasu, Masataka,Lee, Dong-Ung,Wiegrebe, Wolfgang
, p. 1229 - 1238 (2003)
The metabolism of 2,3,10,11-oxygenated protoberberine alkaloids was studied in cell cultures of Corydalis species. Without prior isolation, the structures of the metabolites were determined by LC-MS and LC-NMR analyses. Tetrahydropseudocoptisine α-N-metho salt, pseudoprotopine, and pseudomuramine were identified for the first time, and preliminary evidence for metabolic pathways to the formation of these alkaloids were obtained.
