Phytochemistry p. 1229 - 1238 (2003)
Update date:2022-08-05
Topics:
Isawa, Kinuko
Kuribayashi, Ayako
Sugiura, Makiko
Moriyasu, Masataka
Lee, Dong-Ung
Wiegrebe, Wolfgang
The metabolism of 2,3,10,11-oxygenated protoberberine alkaloids was studied in cell cultures of Corydalis species. Without prior isolation, the structures of the metabolites were determined by LC-MS and LC-NMR analyses. Tetrahydropseudocoptisine α-N-metho salt, pseudoprotopine, and pseudomuramine were identified for the first time, and preliminary evidence for metabolic pathways to the formation of these alkaloids were obtained.
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