6287-19-0

Basic information

• Product Name: 2,4-Dimethylpiperidine
• Synonyms: TIMTEC-BB SBB004310;CIS-2,4-DIMETHYLPIPERIDINE;ART-CHEM-BB B016012;AKOS B016012;2,4-DIMETHYLPIPERIDINE;2,4-LUPETIDINE;2,4-dimethylpiperidine(HCl form)
• CAS NO: 6287-19-0
• Molecular Formula: C₇H₁₅N
• Molecular Weight: 113.2
• Product Categories: Piperidine
• Mol File: 6287-19-0.mol

Chemical Properties

• Boiling Point: 141.2 °C at 760 mmHg
• Flash Point: 28.6 °C
• Appearance: /
• Density: 0.794 g/cm³
• Vapor Pressure: 5.93mmHg at 25°C
• Refractive Index: 1.416
• CAS DataBase Reference: 2,4-Dimethylpiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dimethylpiperidine(6287-19-0)
• EPA Substance Registry System: 2,4-Dimethylpiperidine(6287-19-0)

Safety Data

• Hazardous Substances Data: 6287-19-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis Industry:
2,4-Dimethylpiperidine is used as a chemical intermediate for the synthesis of various complex chemicals. Its presence in the structure of these compounds contributes to their unique properties and applications.
Used in Pharmaceutical Industry:
2,4-Dimethylpiperidine is used as a building block in the development of pharmaceutical compounds. Its structural features allow for the creation of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
2,4-Dimethylpiperidine is used as a precursor in the production of agrochemicals, such as pesticides and herbicides. Its chemical properties enable the creation of effective products for agricultural use.

InChI:InChI=1/C7H15N/c1-6-3-4-8-7(2)5-6/h6-8H,3-5H2,1-2H3

Upstream product

• 108-47-4 2,4-lutidine 
• 64-17-5 ethanol 
• 71-41-0 pentan-1-ol 
• 16728-70-4 3-methyl-5-oxo-hexanenitrile 

Downstream Products

• 67306-34-7 1-{3-[4-(1,1-dimethylethyl)phenyl]-2-methyl-2-propenyl}-2,4-dimethyl-piperidine 

Relevant articles and documents

NOVEL SPIRO IMIDAZOLONE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE

The present invention relates to compounds of the general formula (I): wherein ring A, ring B, G, R3, Z, L1, and L2 are selected independently of each other and are as defined herein, to compositions comprising the compounds, and to methods of using the compounds as glucagon receptor antagonists and for the treatment or prevention of type 2 diabetes and conditions related thereto.

Barriers to Rotation and Inversion in meso-1,1'-Bi(2-methylpiperidine)s

A 13C DNMR study of meso-1,1-bi(2-methylpiperidine) (7), meso-1,1'-bi(cis-2,4-dimethylpiperidine) (8), and meso-1,1'-bi(cis-4-tert-butyl-2-methylpiperidine) (9) with the aid of molecular mechanics calculation of the corresponding hydrocarbons 1,1'-bi(2-methylcyclohexane) (14), 1,1'-bi(cis-2,4-dimethylcyclohexane) (15), and 1,1'-bi(cis-4-tert-butyl-2-methylcyclohexane) (16) is reported.The most stable conformations of the bipiperidines are the enantiomeric conformations in which the lone pairs of the nitrogen atoms are approximately gauche to each other.In these conformations the N-N bond and all of the alkyl groups are equatorial to each of the chair-form piperidine rings.The energy barriers (ΔG*) to the interconversion between these enantiomeric gauche conformations in 7, 8, and 9 are 12.5(-25 deg C), 17.7(+72 deg C), and 19.0 kcal mol-1 (+97 deg C), respectively.While the barrier for 7 is assigned to the passing inversion of the nitrogen atoms, the barriers for 8 and 9 are assigned to the single-passing rotation about the N-N bond.In the case of 7, the next stable conformations, in which one of the methyl groups is axial, were observed at the lower temperatures.The free energy difference between the next stable and the most stable conformations is 0.55 kcal mol-1 at -117 deg C, and the energy barrier between these conformations is 9.2 kcal mol-1 at -82 deg C, which is assigned to the ring inversion.