62885-88-5

Basic information

• Product Name: Acetamide, 2-amino-N-(2-phenylethyl)-
• CAS NO: 62885-88-5
• Molecular Formula: C10H14N2O
• Molecular Weight: 178.234
• Mol File: 62885-88-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acetamide, 2-amino-N-(2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2-amino-N-(2-phenylethyl)-(62885-88-5)
• EPA Substance Registry System: Acetamide, 2-amino-N-(2-phenylethyl)-(62885-88-5)

Safety Data

• Hazardous Substances Data: 62885-88-5(Hazardous Substances Data)

Upstream product

• 55677-50-4 (Phenethylcarbamoyl-methyl)-carbamic acid benzyl ester 
• 64-04-0 phenethylamine 
• 613675-75-5 tert-butyl N-{[(2-phenylethyl)carbamoyl]methyl}carbamate 
• 4746-64-9 2-aminoacetyl chloride 
• 13156-95-1 2-chloro-N-phenethylacetamide 

Downstream Products

• 85221-41-6 (2S,4R)-1-Methyl-4-(phenyl-propionyl-amino)-piperidine-2-carboxylic acid (phenethylcarbamoyl-methyl)-amide 
• 61196-37-0 2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one 
• 55268-74-1 2-cyclohexanecarbonyl-1,2,3,6,7,11b-hexahydro-pyrazino[2,1-a]isoquinolin-4-one 
• 146429-43-8 (N-acetyl-D-asparaginyl)-N-phenethylglycinamide 

Relevant articles and documents

Potent Antifungal Synergy of Phthalazinone and Isoquinolones with Azoles Against Candida albicans

Four phthalazinones (CIDs 22334057, 22333974, 22334032, 22334012) and one isoquinolone (CID 5224943) were previously shown to be potent enhancers of antifungal activity of fluconazole against Candida albicans. Several even more potent analogues of these compounds were identified, some with EC50 as low as 1 nM, against C. albicans. The compounds exhibited pharmacological synergy (FIC 0.5) with fluconazole. The compounds were also shown to enhance the antifungal activity of isavuconazole, a recently FDA approved azole antifungal. Isoquinolone 15 and phthalazinone 24 were shown to be active against several resistant clinical isolates of C. albicans.

Antibody-catalyzed rearrangement of a peptide bond: Mechanistic and kinetic investigations

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