61196-37-0 Usage
Description
1,2,3,6,7,11B-HEXAHYDRO-4H-PYRAZINO(2,1-A)ISOQUINOLINE-4-ONE is a complex organic compound with a unique molecular structure. It is characterized by its hexahydro-pyrazino-isoquinoline framework and a ketone functional group. 1,2,3,6,7,11B-HEXAHYDRO-4H-PYRAZINO(2,1-A)ISOQUINOLINE-4-ONE has potential applications in various fields due to its chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
1,2,3,6,7,11B-HEXAHYDRO-4H-PYRAZINO(2,1-A)ISOQUINOLINE-4-ONE is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
1,2,3,6,7,11B-HEXAHYDRO-4H-PYRAZINO(2,1-A)ISOQUINOLINE-4-ONE is used as a key intermediate in the synthesis of various organic compounds. Its versatile structure allows for further functionalization and modification, making it a useful starting material for the development of new chemical entities with diverse applications.
Used in Research and Development:
1,2,3,6,7,11B-HEXAHYDRO-4H-PYRAZINO(2,1-A)ISOQUINOLINE-4-ONE is used as a research compound in the study of its chemical properties, reactivity, and potential applications. Its unique structure provides opportunities for exploring new reaction pathways and developing innovative synthetic strategies.
Used in the Synthesis of Praziquantel:
1,2,3,6,7,11B-HEXAHYDRO-4H-PYRAZINO(2,1-A)ISOQUINOLINE-4-ONE is used as the main intermediate for synthesizing the antiparasitic agent Praziquantel (P702095). 1,2,3,6,7,11B-HEXAHYDRO-4H-PYRAZINO(2,1-A)ISOQUINOLINE-4-ONE plays a crucial role in the development of this medication, which is used to treat various parasitic infections, including schistosomiasis and tapeworm infections.
Check Digit Verification of cas no
The CAS Registry Mumber 61196-37-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,1,9 and 6 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 61196-37:
(7*6)+(6*1)+(5*1)+(4*9)+(3*6)+(2*3)+(1*7)=120
120 % 10 = 0
So 61196-37-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H14N2O/c15-12-8-13-7-11-10-4-2-1-3-9(10)5-6-14(11)12/h1-4,11,13H,5-8H2
61196-37-0Relevant articles and documents
CONJUGATES
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Page/Page column 77, (2020/07/14)
The present invention provides a conjugate of formula (I) and itsuse in methods of treatment, and also methods for delivering an active agent into a cell. The methods may be used to deliver an active agent into a nematode, flatworm, parasite or bacterium. The conjugate of formula (I) is: (formula (I)), wherein -D- is C1-4 alkylene or C2-4 alkenylene, preferably C2-4 alkenylene, where the alkylene or alkenylene is optionally substituted with alkyl or halo; A- is an active agent for delivery; and -RA, -RB, -RT1, -RT2, -R1, -R2, -R3, -X- and -L- are as defined herein.
Recovery preparation method of racepiquamine
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Paragraph 0080; 0081; 0082; 0085; 0087; 0089; 0091; 0093, (2018/06/12)
The invention discloses a recovery preparation method of racepiquamine-1. The preparation method comprises the following steps: dissolving a waste material S-piquamine intermediate-1 as an initial rawmaterial in a solvent; and carrying out reaction at a proper temperature in the presence of a catalyst and hydrogen at a certain pressure to prepare the piquamine intermediate-1 of racemate. The formula is as shown in the description. The configured piquamine S-1 which is not needed is efficiently, conveniently and fully operated and recovered with a high yield to obtain a racemate compound 1, and then the racemate compound is used again to prepare levopraziquantel, so that wastes can be turned into wealth, and therefore, the generation cost of the levopraziquantel is saved greatly.
One-pot palladium-catalyzed racemization of (S)-praziquanamine: A key intermediate for the anthelmintic agent (R)-praziquantel
Yang, Zhezhou,Guo, Xiang,Xu, Shanghu,Jiao, Huirong,Tan, Zhinmin,Zhang, Fuli
, p. 122 - 130 (2017/03/01)
An one-pot palladium-catalyzed procedure for racemization of (S)-praziquanamine, which is the undesired enantiomer and produced during the resolution step for preparing the anthelmintic drug (R)-praziquantel, has been developed through dehydrogenation of