62907-85-1Relevant academic research and scientific papers
Steric tuning of C2-symmetric chiral N-heterocyclic carbene in gold-catalyzed asymmetric cyclization of 1,6-enynes
Yamada, Ken-Ichi,Matsumoto, Yasumasa,Selim, Khalid B.,Yamamoto, Yasutomo,Tomioka, Kiyoshi
, p. 4159 - 4165 (2012)
Steric tuning of C2-symmetric chiral N-heterocyclic carbene (NHC) was performed in Au(I)-catalyzed asymmetric cyclization of 1,6-enyne. Higher enantioselectivity was realized when chiral NHC-AuCl/AgSbF6 catalysts whose N-substituent on the NHC overlays the Au-Cl bond was utilized.
