6291-17-4

Usage

Uses

Used in Pharmaceutical Synthesis:
3-amino-2-methyl-butan-2-ol is used as a chiral auxiliary for the synthesis of pharmaceuticals and other organic compounds. Its unique structure allows for the creation of enantiomerically pure compounds, which is crucial for the development of effective and safe medications.
Used in Organic Chemical Reactions:
3-amino-2-methyl-butan-2-ol is used as a reagent in organic chemical reactions, particularly those involving asymmetric catalysis. Its presence can enhance the selectivity and yield of desired products, making it a valuable tool in the synthesis of complex organic molecules.
Safety Considerations:
It is important to handle 3-amino-2-methyl-butan-2-ol with appropriate caution and in accordance with safety guidelines to ensure the safety of individuals and the environment. Proper handling, storage, and disposal practices should be followed to minimize potential risks associated with this chemical compound.

InChI:InChI=1/C5H13NO/c1-4(6)5(2,3)7/h4,7H,6H2,1-3H3

Upstream product

• 5076-19-7 trimethyloxirane 
• 917-64-6 methyl magnesium iodide 
• 17344-99-9 AlaOEt 
• 115-22-0 3-Hydroxy-3-methyl-2-butanone 
• 2588-77-4 3-Bromo-2-methyl-2-butanol 
• 21326-62-5 3-chloro-2-methyl-butan-2-ol 
• 7431-25-6 3-hydroxy-3-methyl-butan-2-one oxime 
• 22916-77-4 2-methyl-3-nitro-butan-2-ol 
• 98069-83-1 2-methyl-3-nitroso-2-nitryloxy-butane 
• 513-35-9 2-methyl-but-2-ene 
• 7664-41-7 ammonia 

Downstream Products

• 74608-26-7 (1S)-2-hydroxy-1,2-dimethylpopylamine 
• 600733-91-3 (3R)-3-amino-2-methylbutan-2-ol 
• 563-80-4 3-methyl-butan-2-one 
• 49834-03-9 1,2-dimethyl-2-phenyl-propylamine 
• 30122-47-5 (5-nitro-thiazol-2-yl)-(4,5,5-trimethyl-4,5-dihydro-oxazol-2-yl)-amine 
• 65296-15-3 3-(4-chloro-benzoylamino)-2-methyl-butan-2-ol 
• 50693-29-3 2-(4-chloro-phenyl)-4,5,5-trimethyl-4,5-dihydro-oxazole 
• 1078725-74-2 N-(2-hydroxy-1,2-dimethylpropyl)-3,5-difluoro-4-(2-propynyloxy)benzamide 
• 1237492-36-2 C₁₇H₁₈F₂N₂O₃ 
• 1574395-80-4 7-((S)-2-hydroxy-1,2-dimethyl-propylamino)-[1,6]naphthyridine-2-carboxylic acid [(S)-(3-fluoro-4-methoxy-phenyl)-(1-methyl-1H-pyrazol-4-yl)-methyl]-amide 
• 1574395-79-1 7-((R)-2-hydroxy-1,2-dimethyl-propylamino)-[1,6]naphthyridine-2-carboxylic acid [(S)-(3-fluoro-4-methoxy-phenyl)-(1-methyl-1H-pyrazol-4-yl)-methyl]-amide 

Relevant academic research and scientific papers

INHIBITORS OF JANUS KINASES

The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.

Regio- and diastereoselective formation of 1,2-azidohydroperoxides by photooxygenation of alkenes in the presence of azide anions

1,2-Azidohydroperoxides are accessible from alkenes when irradiated in the presence of azide anions, oxygen and an appropriate sensitizer. The results of substrate/sensitizer variations indicate a reaction initiated by electron transfer to give the sensitizer radical anion and azidyl radicals. The latter efficiently add to alkenes producing carbon radicals which are trapped by molecular oxygen.