62924-18-9

Upstream product

• 79-77-6 4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-2-one 
• 21658-95-7 diisopropyl (cyanomethyl)phosphonate 
• 72214-33-6 3-(2,6,6-Trimethylcyclohex-1-enyl)prop-2-enenitrile 
• 472-80-0 beta-Ionol 
• 53018-97-6 3-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-propenal 
• 62924-17-8 2-Methyl-4-<2',6',6'-trimethyl-1'-cyclohexen-1'-yl>-3-buten-1-ol 
• 143-33-9 sodium cyanide 

Downstream Products

• 20638-88-4 retinonitrile 
• 6980-79-6 (2E,4E,6E)-5-Methyl-7-(2,6,6-trimethyl-cyclohex-1-enyl)-hepta-2,4,6-trienal 
• 99302-33-7 C₁₈⁽¹³⁾CH₂₇NO₂ 
• 99302-32-6 C₁₈⁽¹³⁾CH₂₇NO₂ 
• 87922-15-4 C₁₉⁽¹³⁾CH₂₈O 
• 99302-44-0 C₁₉⁽¹³⁾CH₂₇N 
• 99302-31-5 retinal 
• 99302-30-4 retinal 
• 87922-16-5 C₁₉⁽¹³⁾CH₂₈O 
• 99302-45-1 C₁₉⁽¹³⁾CH₂₇N 
• 99302-43-9 C₁₇⁽¹³⁾CH₂₆O 
• 99302-42-8 C₁₇⁽¹³⁾CH₂₆O 
• 99302-36-0 C₁₆⁽¹³⁾CH₂₃N 
• 99302-34-8 C₁₆⁽¹³⁾CH₂₃N 

Relevant academic research and scientific papers

Synthesis of 8-, 9-, 12-, and 13-mono-13C-retinal

The 8-, 9-, 12-, and 13-mono-13C-retinals were synthesized with >98percent chemical purity and 93percent 13C incorporation from 13C-labelled acetonitrile.Their 13C-13C and 13C-1H nmr coupling constants were determined.

Dihydroretinoic acids and their derivatives. Synthesis and biological activity

The syntheses of the ring and four side-chain dihydroretinoic acids and/or their esters, 3-7, are described. The syntheses of several other retinoids containing a substituted aromatic ring are also included. The biological activity of the compounds was evaluated in vivo in a chemically induced mouse skin papilloma test and in vitro in two vitamin A deficient assays. The activity observed for 1a, 1c, and 2a in the former test was partially retained in the dihydro derivatives 4b, 4c, and 6b. Similar results were found in the in vitro assays.