62940-04-9Relevant academic research and scientific papers
Enamine Chemistry. Part 36. Alkylation of Imines of Medium-Large Ring Ketones with Electrophilic Alkenes
Hickmott, Peter W.,Jutle, Kasturi K.,Pienar, Daniel H.
, p. 2399 - 2402 (2007/10/02)
The alkylation of the benzylamine imines of cycloheptanone, cyclo-octanone, and cyclododecanone with acrylonitrile, methyl acrylate, methyl vinyl sulphone, phenyl vinyl ketone, and phenyl vinyl sulphone, has been studied.The course of the reaction is surp
PRODUCTION OF 3-(2-OXOCYCLODODECYL)PROPIONITRILE FROM CYCLODODECANONE AND ACRYLONITRILE AND SOME OF ITS TRANSFORMATIONS
Zakharkin, L. I.,Churilova, I. M.
, p. 1895 - 1899 (2007/10/02)
A method was developed for the production of 3-(2-oxocyclododecyl)propionitrile by the cyanoethylation of cyclododecanone with acrylonitrile. 2,3-Cyclododecenopyridine was obtained from the oxonitrile by hydrogenation, and 3-(2-oxocyclododecyl)propionamide and 3-(2-oxocyclododecyl)propionic acid were obtained by hydrolysis.When heated with acetic anhydride, the acid forms a mixture of the isomers of 3-oxo-2-oxabicyclohexadec-1(6)-ene.In the presence of perchloric acid the Z and E isomers of 3-oxo-2-bicyclohexadec-1(16)-ene isomerize to 3-oxo-2-oxabicyclohexadec-1(6)-ene.
